Sepsis pp 181-190 | Cite as

Sepsis and Cellular Metabolism

  • G. Gutierrez
Part of the Update in Intensive Care and Emergency Medicine book series (UICM, volume 18)


The cellular and molecular mechanisms of sepsis are unknown. Intense research in the areas of physiology, biochemistry, and cell biology has provided clearer understanding of the causal relationship between bacteria, neutrophils, cytokines, and target cells in sepsis. Knowledge of cellular cytokine interaction [1] has changed our concept of sepsis as an infective process to the more encompassing notion of systemic inflammatory response syndrome (SIRS) [2].


Nitric Oxide Lactic Acidosis Tissue Hypoxia Cecal Ligation Arterial Lactate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer-Verlag Berlin Heidelberg 1994

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  • G. Gutierrez

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