Abstract
Invasion of the body by pathogens, or trauma and chronic neoplastic and inflammatory disease, brings about activation of the immune system. A range of molecules with high biological potency are produced by the system, with the objective of defeating the invasion, destroying damaged and aberrant cells, and restoring tissue function to normal. Cytokines, free radicals and other oxidant products are among these potent molecules. The cytokines comprise the interleukins 1–12 (IL1-12), tumour necrosis factors (TNF) and interferons [1]. Free radicals comprise the superoxide, hydroxyl and nitric oxide radicals. Other oxidant products which are related to free radical biology are hypochlorous acid and hydrogen peroxide [2, 3].
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Grimble, R.F. (1993). The Maintenance of Antioxidant Defenses during Inflammation. In: Wilmore, D.W., Carpentier, Y.A. (eds) Metabolic Support of the Critically Ill Patient. Update in Intensive Care and Emergency Medicine, vol 17. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85011-0_20
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DOI: https://doi.org/10.1007/978-3-642-85011-0_20
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