Present Status of EORTC Trials of Hyperfractionated and Accelerated Radiotherapy on Head and Neck Carcinoma

  • J. C. Horiot
  • A. C. Begg
  • R. Le Fur
  • S. Schraub
  • W. van den Bogaert
  • M. van Glabbeke
  • M. Pierart
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 134)

Abstract

The European Organization for Research on Treatment of Cancer (EORTC) Cooperative Group of Radiotherapy started phase II and III trials on modified fractionation schemes in 1980. As of June 1, 1992, 2006 patients have entered eight trials. This short overview will only concentrate on two phase III trials of hyperfractionation (EORTC trial 22791) and accelerated fractionation (trial 22851).

Keywords

Toxicity Pancreatitis Fractionation Oncol Stratification 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1994

Authors and Affiliations

  • J. C. Horiot
    • 1
  • A. C. Begg
    • 2
  • R. Le Fur
    • 3
  • S. Schraub
    • 4
  • W. van den Bogaert
    • 5
  • M. van Glabbeke
    • 6
  • M. Pierart
    • 6
  1. 1.Tumor Institute Centre G.F. LeclercDijonFrance
  2. 2.Tumor Institute A. van LeeuwenhoekhuisAmsterdamThe Netherlands
  3. 3.Tumor Institute Centre H. BecquerelRouenFrance
  4. 4.University Hospital Jean MinjozBesançonFrance
  5. 5.University Hospital Sint RafaelLeuvenBelgium
  6. 6.European Organization for Research on Treatment of Cancer Data CentreBrusselsBelgium

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