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Nonhuman Primates pp 138–142Cite as

Pyrophosphate Arthropathy, Macaca mulatta

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Part of the book series: Monographs on Pathology of Laboratory Animals ((LABORATORY))

Abstract

Pseudogout is a disease of the joints and intervertebral disc and is associated with chronic degenerative joint disease of primarily the knee articular cartilage and menisci. Cartilage changes are characterized by marginal erosion of cartilage, ulceration, fibrillation of articular cartilage and osteophyte formation (Fig. 149). The chronic knee joint changes are also associated with muscle and tendon contraction, which prevents the extension of the knee joint. If sufficient quantity of the pyrophosphate crystals are present, a focal whitish discoloration of the cartilage or menisci will be evident (Fig. 149). Radiographically, focal radio-densities may be observed in the affected tissues (Kessler et al. 1986).

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Authors
  1. E. Donald Roberts
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Editors and Affiliations

  1. Harvard Medical School, ILSI Research Foundation, 1126 Sixteenth Street, N. W., Washington, DC, 20036, USA

    Thomas Carlyle Jones D. V.M., D.Sc. (Professor of Comparative Pathology, Emeritus) (Professor of Comparative Pathology, Emeritus)

  2. Institut für Experimentelle Pathologie, Medizinische Hochschule Hannover, Konstanty-Gutschow-Strasse 8, 30625, Hannover, Federal Republic of Germany

    Ulrich Mohr M. D. (Professor of Experimental Pathology) (Professor of Experimental Pathology)

  3. New England Regional Primate Research Center, Harvard Medical School, One Pine Hill Drive, Southborough, MA, 01772, USA

    Ronald Duncan Hunt D. V.M. (Professor of Comparative Pathology) (Professor of Comparative Pathology)

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© 1993 Springer-Verlag Berlin Heidelberg

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Roberts, E.D. (1993). Pyrophosphate Arthropathy, Macaca mulatta . In: Jones, T.C., Mohr, U., Hunt, R.D. (eds) Nonhuman Primates. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84924-4_29

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  • DOI: https://doi.org/10.1007/978-3-642-84924-4_29

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-84926-8

  • Online ISBN: 978-3-642-84924-4

  • eBook Packages: Springer Book Archive

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