Vitamin C Deficiency, Old and New World Monkeys
The response to vitamin C deficiency differs between the various primate species. The naturally occurring disease in squirrel monkeys (Saimiri sciureus) appears to involve mainly the head region, whereas in rhesus macaques (Macaca mulatta) the disease involves the long bones, teeth, and ribs. Petechiae to ecchymoses of gingiva, nasal cavity, subcutaneous tissue, and periosteum are basic lesions as vitamin C is essential to the production of collagen fibrils which are common to both vascular integrity and osteoid formation. In the squirrel monkey, the deficiency is manifest by pericranial hemorrhage forming large hematomas. The hematomas give the animal’s head the appearance of a “turban” and stretch and distort the facial features (Fig. 219).
KeywordsPermeability Obesity Anemia Fibril Hunt
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