Herpesvirus platyrrhinae Infection
The pathological and biological features of Herpesvirus T infection are remarkably similar to Herpesvirus simplex infection as described on p. 82, this volume. The virus, however, is distinct and only New World monkeys are naturally affected (Holmes et al. 1964; Melnick et al. 1964). Herpesvirus T is carried by squirrel monkeys (Saimiri sciureus) (Mélendez et al. 1966) in which serum antibodies are very frequent but clinical disease only rarely recorded. Documented lesions in squirrel monkeys consist of vesicles and ulcers of the oral mucous membranes and lips and have a very similar gross and microscopic appearance to H. simplex lesions in human beings (Figs. 100-105) (Daniel et al. 1967; King et al. 1967). Circulating serum neutralizing antibodies to Herpesvirus T have been detected also in cinnamon ringtail monkeys (Cebus albifrons) and spider monkeys (Ateles spp.), which might also be natural reservoir hosts but no clinical disease has been described in these two species (Holmes et al. 1966).
KeywordsHunt Adenine Encephalitis Monophosphate Acyclovir
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- Mélendez LV, Hunt RD, Garcia FG, Trum BF (1966) A latent Herpes T infection in Saimiri sciureus (squirrel monkey). In: Fiennes RN, Fiennes TW (eds) Recent developments in comparative medicine. Academic, London, pp 393–397Google Scholar