Diagnosis of Radiation-Pneumonitis

  • G. Sigmund
  • J. Slanina
  • W. Hinkelbein
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 130)

Abstract

The pulmonary radioreaction is an interstitial pulmonary inflammation, so-called pneumonitis, which to a certain degree has an intraalveolar exudative component. If the threshold of potential complete restitution is crossed, the pneumonitis will develop into pulmonary fibrosis (a scar) as a permanent residual (Gross 1977; Slanina et al. 1977; Westcott and Cole 1986; White 1975).

Keywords

Lymphoma Corticosteroid Shrinkage Oncol Gadolinium 

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References

  1. Coscina WF, Arger PH, Mintz MC, Coleman BG (1986) CT demonstration of pulmonary effects of tangential beam irradiation. J Comput Assist Tomogr 10: 600–602PubMedCrossRefGoogle Scholar
  2. Frija J, Fermé C, Baud L, Gisselbrecht C, Miot C, Fermand JP, Laval-Jeantet M (1988) Radiation-induced lung injuries: a survey by computed tomography and pulmonary function tests in 18 cases of Hodgkin’s disease. Eur J Radiol 8: 18–23PubMedGoogle Scholar
  3. Glazer HS, Lee JKT, Levitt RG, Heiken JP, Ling D, Totty WG, Balfe DM, Emani B, Wasserman TH, Murphy WA (1986) Radiation fibrosis: differentiation from recurrent tumor by MR imaging. Work in progress. Radiology 156: 721–726Google Scholar
  4. Gross NJ (1977) Pulmonary effects of radiation therapy. Ann Intern Med 86: 81–92PubMedGoogle Scholar
  5. Heron CW, Husband JE, Williams MP, Cherryman GR (1988) The value of thoracic computed tomography in the detection of recurrent Hodgkin’s disease. Br J Radiol 61: 567–572PubMedCrossRefGoogle Scholar
  6. Ikezoe J, Takashima S, Morimoto S, Kadowaki K, Takeuchi N, Yamamoto T, Nakanishi K, Isaza M, Arisawa J, Ikeda H, Masaki N, Kozuka T (1988) CT appearance of acute radiation-induced injury in the lung. AJR 150: 765–770PubMedGoogle Scholar
  7. Lever AML, Henderson D, Ellis DA, Corns PA, Gilmartin JJ (1984) Radiation fibrosis mimicking local recurrence in small cell carcinoma of the bronchus. Br J Radiol 57: 178–180PubMedCrossRefGoogle Scholar
  8. Libshitz HI, Shuman LS (1984) Radiation-induced pulmonary changes: CT findings. J Comput Assist Tomogr 1984; 8: 15–19CrossRefGoogle Scholar
  9. Mah K, van Dyk J (1988) Quantitative measurement of changes in human lung density following irradiation. Radiother Oncol 11: 169–179PubMedCrossRefGoogle Scholar
  10. Mah K, Poon PY, van Dyk J, Keane T, Majesky IF, Rideout DF (1986) Assessment of acute radiation-induced pulmonary changes using computed tomography. J Comput Assist Tomogr 10: 736–743PubMedCrossRefGoogle Scholar
  11. Nabawi P, Mantravadi R, Breyer D, Capek V (1981) Computed tomography of radiation-induced lung injuries. J Comput Assist Tomogr 5: 568–570PubMedCrossRefGoogle Scholar
  12. Naidich DP, Zerhouni EA, Siegelman SS (1984a) Computed tomography of the thorax. Raven, New York, p 134Google Scholar
  13. Naidich DP, Zerhouni EA, Siegelman SS (1984b) Computed tomography of the thorax. Raven, New York, p 205Google Scholar
  14. Pagani JJ, Libshitz HI (1982) CT manifestations of radiation-induced change in chest tissue. J Comput Assist Tomogr 6: 243–248PubMedCrossRefGoogle Scholar
  15. Shea WJ, deGeer G, Webb WR (1987) Chest wall after mastectomy. I. CT appearance of normal postoperative anatomy, post-irradiation changes, and optimal scanning techniques. Radiology 162: 157–161PubMedGoogle Scholar
  16. Slanina J, Musshoff K, Rahner T, Stiasny R (1977) Long-term side effects in irradiated patients with Hodgkin’s disease. Int J Radiat Oncol Biol Phys 2: 1–19PubMedGoogle Scholar
  17. Slanina J, Wannenmacher M, Bruggmoser G, Krüger HU (1982) Die pulmonale Strahlenreaktion im Röntgenbild. (Pulmonary radioreaction demonstrated by X-ray pictures.) Radiologe 22:74–82 (In German, with English summary)PubMedGoogle Scholar
  18. Slanina J, Maschitzki R, Wannenmacher M (1987) Die pulmonale Strahlenreaktion im Röntgenbild des Thorax nach Megavolttherapie bei Mammakarzinom. (Pulmonary reaction to radiation as seen on chest X-ray following megavolt therapy for carcinoma of the breast). Radiologe 27: 181–191 (In German, with English summary)PubMedGoogle Scholar
  19. Slanina J, Sigmund G, Hinkelbein W, Wenz W, Wannenmacher M (1988) Die pulmonale Strahlenreaktion nach Mantelfeldbestrahlung: Vergleich der Verlaufsstadien im konventionellen Röntgenbild and im Computertomogramm. (Radiation-induced pulmonary changes after mantle-field irradiation: comparison of consecutive stages in chest radiography and computed tomography.) Radiologe 28:20–28 (In German, with English summary)Google Scholar
  20. Westcott JL, Cole SR (1986) Traction bronchiectasis in end-stage pulmonary fibrosis. Radiology 161: 665–669PubMedGoogle Scholar
  21. White DC (1975) An atlas of radiation histopathology. US Energy Research Development Administration, Government Printing Office, Washington, DCGoogle Scholar

Copyright information

© Springer-Verlag Berlin · Heidelberg 1993

Authors and Affiliations

  • G. Sigmund
    • 1
  • J. Slanina
    • 2
  • W. Hinkelbein
    • 2
  1. 1.Department of Diagnostic RadiologyUniversity of FreiburgFreiburg i. Br.Fed. Rep. of Germany
  2. 2.Department of Radiotherapy, Radiologic ClinicUniversity of FreiburgFreiburg i. Br.Fed. Rep. of Germany

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