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Acute and Long-Term Side-Effects of Radiotherapy pp 109–121Cite as

Radiopathology of the Lung: Experimental and Clinical Observations

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Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 130))

Abstract

More than 40 cell types are found in the lung, most of which are considered to be relatively radioresistant. However, the lung is unable to tolerate large radiation doses since the organ as a whole has little regenerative capacity. Ionizing radiation causes immediate alterations at the biochemical, subcellular, and cellular level. Gross tissue injury associated with organ dysfunction is delayed: symptomatic pneumonitis occurs at about 1 to several months after irradiation, fibrosis after 6 months to 1 year.

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Authors and Affiliations

  1. Klinik für Strahlentherapie, Technische Universität, W-8000, München, Fed. Rep. of Germany

    M. Molls

  2. Radiologisches Zentrum, Medizinische Akademie, O-8019, Dresden, Fed. Rep. of Germany

    Th. Herrmann

  3. Radiologisches Zentrum, Universitätsklinikum, W-4300, Essen, Fed. Rep. of Germany

    F. Steinberg & H. J. Feldmann

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  1. M. Molls
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  2. Th. Herrmann
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  3. F. Steinberg
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  4. H. J. Feldmann
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Editors and Affiliations

  1. Abteilung Strahlentherapie, Radiologische Universitätsklinik, Hugstetter Strasse 55, W-7800, Freiburg, Germany

    Wolfgang Hinkelbein , Gregor Bruggmoser  & Hermann Frommhold ,  & 

  2. Abteilung Radiologie, Radiologische Universitätsklinik, Im Neuenheimer Feld 400, W-6900, Heidelberg, Germany

    Michael Wannenmacher

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© 1993 Springer-Verlag · Berlin Heidelberg

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Molls, M., Herrmann, T., Steinberg, F., Feldmann, H.J. (1993). Radiopathology of the Lung: Experimental and Clinical Observations. In: Hinkelbein, W., Bruggmoser, G., Frommhold, H., Wannenmacher, M. (eds) Acute and Long-Term Side-Effects of Radiotherapy. Recent Results in Cancer Research, vol 130. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84892-6_10

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