Aggressive Abdominal Lymphoma
A 76-year-old man presented with lower gastrointestinal (GI) bleeding. The cause was a diffuse non-Burkitt’s lymphoma of the terminal ileum which had perforated. While a resection was performed, disease remained around the right ureter and invaded the small bowel and mesentery. He had lost 20 lbs. Two months after the completion of six courses of cyclophosphamide, hydroxydaunomycin (doxorubicin), Oncovin (vincristine) (CHOP), a very large (12×12×6 cm) right lower quadrant subcutaneous mass was biopsied and diffuse non-Burkitt’s lymphoma was diagnosed. The mass grew during treatment with etoposide (VP-16) and prednisone.