Pathology of Human Cytomegalovirus Infection

  • Harry V. Vinters
  • Jorge A. Ferreiro
Part of the Frontiers of Virology book series (FRVIROLOGY, volume 2)

Summary

Cytomegalovirus (CMV) produces widely variable pathologic change in infected tissues, whether in the context of acquired immunodeficiency syndrome (AIDS) or another form of immunosuppression, e.g., that noted after organ or bone marrow transplantation. Characteristic cytomegalic cells may be present with minimal or absent inflammatory response in a given organ, or there may be extensive associated inflammation and necrosis with clinically significant dysfunction. This chapter discusses and illustrates the histologic manifestations of CMV infection in the context of their clinical presentation, and complements other chapters that discuss molecular mechanisms of CMV pathogenesis and neuropathogenesis.

Keywords

Lymphoma Leukemia Neurol Cyclophosphamide Perforation 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • Harry V. Vinters
    • 1
    • 2
  • Jorge A. Ferreiro
    • 1
  1. 1.Department of Pathology, Los Angeles Medical CenterUniversity of CaliforniaLos AngelesUSA
  2. 2.Brain Research Institute, Los Angeles Medical CenterUniversity of CaliforniaLos AngelesUSA

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