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The Control of Cytomegalovirus Infection: Chemotherapy

  • Chapter
Molecular Aspects of Human Cytomegalovirus Diseases

Part of the book series: Frontiers of Virology ((FRVIROLOGY,volume 2))

Abstract

The pharmacokinetic profile, efficacy and toxicity of the two principal chemotherapeutic agents, ganciclovir and foscarnet, utilized in the treatment of cytomegalovirus infection in the immunocompromised host are reviewed. In addition, the efficacy, cost and safety of the various prophylactic regimens for prevention of cytomegalovirus disease is examined. Recommendations for treatment and prophylaxis in HIV infected and transplant recipients are given.

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Authors and Affiliations

  1. Division of Infectious Disease, University of North Carolina, Campus Box # 7030, Chapel Hill, NC, 27599-7030, USA

    Jonathan S. Serody & Charles M. van der Horst

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  1. Jonathan S. Serody
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  2. Charles M. van der Horst
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Editors and Affiliations

  1. Department of Molecular Virology, Faculty of Medicine, Hebrew University of Jerusalem, POB 1172, 910010, Jerusalem, Israel

    Yechiel Becker

  2. Institut für Medizinische Virologie, Universität Heidelberg, Im Neuenheimer Feld 324, W-6900, Heidelberg, Germany

    Gholamreza Darai

  3. Lineberger Comprehensive Cancer Research Center, The University of North Carolina, CB # 7259, Rm. 117, Lineberger Building, 27599-7295, Chapel Hill, NC, USA

    Eng-Shang Huang Ph. D.

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© 1993 Springer-Verlag Berlin Heidelberg

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Serody, J.S., van der Horst, C.M. (1993). The Control of Cytomegalovirus Infection: Chemotherapy. In: Becker, Y., Darai, G., Huang, ES. (eds) Molecular Aspects of Human Cytomegalovirus Diseases. Frontiers of Virology, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84850-6_14

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  • DOI: https://doi.org/10.1007/978-3-642-84850-6_14

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  • Online ISBN: 978-3-642-84850-6

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