Human Papillomavirus Types 6 and 11 in Tumours

  • R. L. Bryan
  • J. Crocker
Part of the Frontiers of Virology book series (FRVIROLOGY, volume 1)

Summary

Human papillomavirus (HPV) types 6 and 11 are known to be associated with tumours of the upper respiratory tract and anogenital region. Their presence has been demonstrated by a variety of techniques, particularly in benign tumours at these sites. The extremely sensitive polymerase chain reaction indicates that these viruses are more widespread than was previously thought; they are frequently associated with malignant tumours and also with tissue showing no histological abnormality.

Keywords

Adenocarcinoma Dimethyl Paraffin Gelatin Ethidium 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Abramson AL, Steinberg BM, Winkler B (1987) Laryngeal papillomatosis: clinical, histologic and molecular studies. Laryngoscope 97:678–685PubMedCrossRefGoogle Scholar
  2. Boyle WF, Riggs JL, Oshiro LS, Lennette EH (1973) Electron microscopic identification of papova virus in laryngeal papilloma. Laryngoscope 83:1102–1108PubMedCrossRefGoogle Scholar
  3. Brandwein M, Steinberg B, Thung S, Biller H, Dilorenzo T, Galli R (1989) Human papillomavirus 6/11 and 16/18 in Schneiderian inverted papillomas. In situ hybridization with human papillomavirus RNA probes. Cancer 63:1708–1713Google Scholar
  4. Braun L, Kashima H, Eggleston J, Shah K (1982) Demonstration of papillomavirus antigen in paraffin section of a laryngeal papilloma. Laryngoscope 92:640–643PubMedCrossRefGoogle Scholar
  5. Bryan RL, Bevan IS, Crocker J, Young LS (1990) Detection of HPV 6 and 11 in tumours of the upper respiratory tract using the polymerase chain reaction. Clin Otolaryngol 15:177–180PubMedCrossRefGoogle Scholar
  6. Crum CP, Mitao M, Levine RU, Silverstein S (1985) Cervial papillomaviruses segregate within morphologically distinct precancerous lesions. J Virol 54:675–681PubMedGoogle Scholar
  7. de Villiers EM, Schneider A, Gross G, zur Hausen H (1986) Analysis of benign and malignant urogenital tumours for human papillomavirus infection by labelling cellular DNA. Med Microbiol Immunol (Berl) 174:281–286PubMedCrossRefGoogle Scholar
  8. Del Mistro A, Braunstein JD, Halwer M, Koss LG (1987) Identification of human papillomavirus types in male urethral condylomata acuminata by in situ hybridisation. Hum Pathol 18:936–940PubMedCrossRefGoogle Scholar
  9. Doorbar J, Gallimore PH (1987) Identification of the proteins encoded by the LI and L2 open reading frames of human papillomavirus la. J Virol 61:2793–2799PubMedGoogle Scholar
  10. Duggan MA, Lim M, Gill MJ, Inoue M (1990) HPV DNA typing of adult-onset respiratory papillomatosis. Laryngoscope 100:639–642PubMedCrossRefGoogle Scholar
  11. Firzlaff JM, Kiviat NB, Beckmann AM, Jenison SA, Galloway DA (1988) Detection of human papillomavirus capsid antigens in various squamous epithelial lesions using antibodies directed against the LI and L2 open reading frames. Virology 164:467–477PubMedCrossRefGoogle Scholar
  12. Friedman JM, Fialkow PJ (1976) Viral “tumorigenesis” in man: cell markers in condylomata acuminata. Int J Cancer 17:57–61PubMedCrossRefGoogle Scholar
  13. Gissmann L, zur Hausen H (1980) Partial characterization of viral DNA from human genital warts (condylomata acuminata). Int J Cancer 25:605–609PubMedCrossRefGoogle Scholar
  14. Gissmann L, de Villiers EM, zur Hausen H (1982 a) Analysis of human genital warts (condylomata acuminata) and other genital tumors for human papillomavirus type 6 DNA. Int J Cancer 29:143–146PubMedCrossRefGoogle Scholar
  15. Gissmann L, Diehl V, Schulz-Coulon HJ, zur Hausen H (1982 b) Molecular cloning and characterization of human papillomavirus DNA derived from a laryngeal papilloma. J Virol 44:393–400PubMedGoogle Scholar
  16. Gissmann L, Wolnik L, Ikenberg H, Koldovsky U, Schnurch HG, zur Hausen H (1983) Human papillomavirus types 6 and 11 DNA sequences in genital and laryngeal papillomas and in some cervical cancers. Proc Natl Acad Sci USA 80:560–563PubMedCrossRefGoogle Scholar
  17. Griffin NR, Bevan IS, Lewis FA, Wells M, Young LS (1990) Demonstration of multiple HPV types in normal cervix and in cervical squamous cell carcinoma using the polymerase chain reaction on paraffin wax embedded material. J Clin Pathol 43:52–56PubMedCrossRefGoogle Scholar
  18. Grussendorf-Conen El, Deutz FJ, de Villiers EM (1987) Detection of human papillomavirus-6 in primary carcinoma of the urethra in men. Cancer 60:1832–1835PubMedCrossRefGoogle Scholar
  19. Gupta JW, Saito K, Saito A, Fu YS, Shah KV (1989) Human papillomaviruses and the pathogenesis of cervical neoplasia. A study by in situ hybridization. Cancer 64:2104–2110Google Scholar
  20. Jenkins D, Tay SK, McCance DJ, Campion MJ, Clarkson PK, Singer A (1986) Histological and immunocytochemical study of cervical intraepithelial neoplasia (CIN) with associated HPV 6 and HPV 16 infections. J Clin Pathol 39:1177–1180PubMedCrossRefGoogle Scholar
  21. Judd R, Zaki SR, Coffield LM, Evatt BL (1991) Sinonasal papillomas and human papillomavirus: human papillomavirus 11 detected in fungiform Schneiderian papillomas by in situ hybridization and the polymerase chain reaction. Hum Pathol 22:550–556PubMedCrossRefGoogle Scholar
  22. Kasher MS, Roman A (1988) Characterization of human papillomavirus type 6b DNA isolated from an invasive squamous carcinoma of the vulva. Virology 165:225–233PubMedCrossRefGoogle Scholar
  23. Kerley SW, Persons DL, Fishback JL (1991) Human papillomavirus and carcinoma of the urinary bladder. Mod Pathol 4:316–319PubMedGoogle Scholar
  24. Klug A, Finch JT (1965) Structure of viruses of the papilloma-polyoma type: 1. Human wart virus. J Mol Biol 11:403–423Google Scholar
  25. Koss LG, Durfee GR (1956) Unusual patterns of squamous epithelium of the uterine cervix: cytologie and pathologic study of koilocytotic atypia. Ann NY Acad Sci 63:1245–1261PubMedCrossRefGoogle Scholar
  26. Kreider JW, Howett MK, Wolfe SA, Bartlett GL, Zaino RJ, Sedlacek TV, Mortel R (1985) Morphological transformation in vivo of human uterine cervix with papillomavirus from condylomata acuminata. Nature 317:639–641PubMedCrossRefGoogle Scholar
  27. Kulke R, Gross GE, Pfister H (1989) Duplication of enhancer sequences in human papillomavirus 6 from condylomas of the mamilla. Virology 173:284–290PubMedCrossRefGoogle Scholar
  28. Loke SL, Ma L, Wong M, Srivastava G, Lo I, Bird CC (1990) Human papillomavirus in oesophageal squamous cell carcinoma. J Clin Pathol 43:909–912PubMedCrossRefGoogle Scholar
  29. Masood S, Rhatigan RM, Powell S, Thompson J, Rodenroth N (1991) Human papillomavirus in prostatic cancer: no evidence found by in situ DNA hybridization. South Med J 84:235–236PubMedCrossRefGoogle Scholar
  30. McCance DJ (1986) Human papillomaviruses and cancer. Biochim Biophys Acta 823:195–205PubMedGoogle Scholar
  31. McLellan R, Buscema J, Guerrero E, Shah KV, Woodruff JD, Currie JL (1990) Investigation of ovarian neoplasia of low malignant potential for human papillomavirus. Gynecol Oncol 38:383–385PubMedCrossRefGoogle Scholar
  32. McLeod K (1987) Prediction of human papilloma virus antigen in cervical squamous epithelium by koilocyte nuclear morphology and “wart scores”: confirmation by immunoper-oxidase. J Clin Pathol 40:323–328PubMedCrossRefGoogle Scholar
  33. Melchers WJG, Schift R, Stolz E, Lindeman J, Quint WGV (1989) Human papillomavirus detection in urine samples from male patients by the polymerase chain reaction. J Clin Microbiol 27:1711–1714PubMedGoogle Scholar
  34. Mevorach RA, Cos LR, di Sant’Agnese PA, Stoler M (1990) Human papillomavirus type 6 in grade I transitional cell carcinoma of the urethra. J Urol 143:126–128PubMedGoogle Scholar
  35. Mittal KR, Chan W, Demopoulos RI (1990) Sensitivity and specificity of various morphological features of cervical condylomas. An in situ hybridization study. Arch Pathol Lab Med 114:1038–1041Google Scholar
  36. O’Brien WM, Jenson AB, Lancaster WD, Maxted WC (1989) Human papillomavirus typing of penile condyloma. J Urol 141:863–865PubMedGoogle Scholar
  37. Oriel JD (1971) Natural history of genital warts. Br J Vener Dis 47:1–13PubMedGoogle Scholar
  38. Oriel JD, Almeida JD (1970) Demonstration of virus particles in human genital warts. Br J Vener Dis 46:37–42PubMedGoogle Scholar
  39. Padel AF, Venning VA, Evans MF, Quantrill AM, Fleming KA (1990) Human papillomaviruses in anogenital warts in children: typing by in situ hybridisation. Br Med J 300:1491–1494CrossRefGoogle Scholar
  40. Pfister H (1987) Human papillomaviruses and genital cancer. Adv Cancer Res 48:113–147PubMedCrossRefGoogle Scholar
  41. Quiney RE, Wells M, Lewis FA, Terry RM, Michaels L, Croft CB (1989) Laryngeal papillomatosis; correlation between severity of disease and presence of HPV 6 and 11 detected by in situ DNA hybridisation. J Clin Pathol 42:694–698PubMedCrossRefGoogle Scholar
  42. Rando RF, Groff DE, Chirikjian JG, Lancaster WD (1986) Isolation and characterization of a novel human papillomavirus type 6 DNA from an invasive vulvar carcinoma. J Virol 57:353–356PubMedGoogle Scholar
  43. Schwarz E, Durst M, Demankowski C, Lattermann O, Zech R, Wolfspender E, Suhai S, zur Hausen H (1983) DNA sequence and genome organization of genital human papillomavirus type 6b. EMBO J 2:2341–2348PubMedGoogle Scholar
  44. Sedlacek TV, Lindheim S, Eder C, Hasty L, Woodland M, Ludomirsky A, Rando RF (1989) Mechanism for human papillomavirus transmission at birth. Am J Obstet Gynecol 161:55–59PubMedGoogle Scholar
  45. Sekine H, Fuse A, Inaba N, Takamizawa H, Simizu B (1989) Detection of the human papillomavirus 6 b E2 gene product in genital condyloma and laryngeal papilloma tissues. Virology 170:92–98PubMedCrossRefGoogle Scholar
  46. Skyldberg B, Kalantari M, Karki M, Johansson B, Hagmar B, Walaas L (1991) Detection of human papillomavirus infection in tissue blocks by in situ hybridization as compared with a polymerase chain reaction procedure. Hum Pathol 22:578–582PubMedCrossRefGoogle Scholar
  47. Steinberg BM, Meade R, Kalinowski S, Abramson AL (1990) Abnormal differentiation of human papillomavirus-induced laryngeal papillomas. Arch Otolaryngol Head Neck Surg 116:1167–1171PubMedCrossRefGoogle Scholar
  48. Terry RM, Lewis FA, Robertson S, Blythe D, Wells M (1989) Juvenile and adult laryngeal papillomata: classification by in situ hybridization for human papillomavirus. Clin Otolaryngol 14:135–139PubMedCrossRefGoogle Scholar
  49. Tsutsumi K, Nakajima T, Gotoh M, Shimosato Y, Tsunokawa Y, Terada M, Ebihara S, Ono I (1989) In situ hybridization and immunohistochemical study of human papillomavirus infection in adult laryngeal papillomas. Laryngoscope 99:80–85PubMedCrossRefGoogle Scholar
  50. Weaver MG, Abdul-Karim FW, Dale G, Sorensen K, Huang YT (1990) Outcome in mild and moderate cervical dysplasias related to the presence of specific human papillomavirus types. Mod Pathol 3:679–683PubMedGoogle Scholar
  51. Wright RG, Murthy DP, Gupta AC, Cox N, Cooke RA (1990) Comparative in situ hybridisation of juvenile laryngeal papillomatosis in Papua New Guinea and Australia. J Clin Pathol 43:1023–1025PubMedCrossRefGoogle Scholar
  52. Young FI, Ward LM, Brown LJR (1991) Absence of human papilloma virus in cervical adenocarcinoma determined by in situ hybridisation. J Clin Pathol 44:340–341PubMedCrossRefGoogle Scholar
  53. Young LS, Bevan IS, Johnson MA, Blomfield PI, Bromidge T, Maitland NJ, Woodman CBJ (1989) The polymerase chain reaction: a new epidemiological tool for investigating cervical human papillomavirus infection. Br Med J 298:14–18CrossRefGoogle Scholar
  54. zur Hausen H (1987) Papillomaviruses in human cancer. Cancer 59:1692–1696PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • R. L. Bryan
    • 1
  • J. Crocker
    • 1
  1. 1.Department of HistopathologyEast Birmingham HospitalBirminghamUK

Personalised recommendations