From the Overview to the Patient: How To Interpret Meta-analysis Data

  • R. D. Gelber
  • A. Goldhirsch
Conference paper
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 127)

Abstract

Clinical investigators have not easily accepted the concept of meta-analysis. Those who perform these formal statistical combinations of data from several different trials have been referred to as “those burgeoning band of interlopers, the meta-analysts” [1]. Critics have referred to meta-analysis as “pooling, drowning, and floating” in the past [2], and even today many view the exercise as potentially dangerous, and clearly a threat to the integrity and importance of the individual clinical trial [3, 4].

Keywords

Estrogen Tamoxifen 

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Copyright information

© Springer-Verlag Berlin · Heidelberg 1993

Authors and Affiliations

  • R. D. Gelber
    • 1
  • A. Goldhirsch
    • 2
  1. 1.Harvard Medical School, Harvard School of Public HealthDana-Farber Cancer InstituteBostonUSA
  2. 2.International Breast Cancer Study GroupOspedale CivicoLuganoSwitzerland

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