Prevention of Bronchopulmonary Dysplasia by New Ventilatory Techniques

  • A. Pardou
  • J. M. Bouton
Conference paper
Part of the Yearbook of Intensive Care and Emergency Medicine book series (YEARBOOK, volume 1992)

Abstract

Improvement in the care of premature infants, particularly due to more sophisticated ventilation and monitoring techniques, has increased the numbers of babies surviving, even as young as 24 weeks of gestation. Many of these preterm newborn babies develop a respiratory distress syndrome due to hyaline membrane disease within the first few hours of birth: uncomplicated hyaline membrane disease is self limiting and resolves in 7 to 10 days, but complicated hyaline membrane disease leads to bronchopulmonary dysplasia or chronic lung disease (CLD).

Keywords

Surfactant Toxicity Dioxide Helium Respiration 

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References

  1. 1.
    Northway WH, Rosan RC, Porter DY (1967) Pulmonary disease following respiratory therapy of hyaline membrane disease: bronchopulmonary dysplasia. N Engl J Med 267:357–368CrossRefGoogle Scholar
  2. 2.
    Horbar JD, McAuliffe TL, Adler SM et al. (1988) Variability in 28 days outcome for very low birth weight infants: an analysis of 11 neonatal intensive care units. Pediatrics 82:554–559PubMedGoogle Scholar
  3. 3.
    Avery GB (1990) Bronchopulmonary dysplasia. In: Decker BC (ed) Current therapy in neonatal-perinatal medicine-2, pp. 188–192Google Scholar
  4. 4.
    Sinkin RA, Cox C, Phelps DL (1990) Predicting risk for bronchopulmonary dysplasia: selection criteria for clinical trials. Pediatrics 86:728–736PubMedGoogle Scholar
  5. 5.
    Gerstmann DR, deLemos RA, Clark RH (1991) High-frequency ventilation: issues of strategy. Clin Perinat 18:563–580Google Scholar
  6. 6.
    Murdock AI, Kidd BSL, Llewellyn MA, et al. (1970) Intrapulmonary venous admixture in the respiratory distress syndrome. Biol Neonate 15:1–7PubMedCrossRefGoogle Scholar
  7. 7.
    Hird MF, Greenough A (1991) Comparison of triggering systems for neonatal patient triggered ventilation. Arch Dis Child 66:426–428PubMedCrossRefGoogle Scholar
  8. 8.
    Avery ME, Tooley WH, Keller JB et al. (1987) Is chronic lung disease in low birth weight infants preventable? A survey of eight centers. Pediatrics 79:26–30PubMedGoogle Scholar
  9. 9.
    Carlo WA, Pacifico L, Chatburn RL, Fanaroff AA (1986) Efficacy of computer-assisted management of respiratory failure in neonates. Pediatrics 78:139–143PubMedGoogle Scholar
  10. 10.
    Fuhrman BP, Paczan PR, DeFrancisis M (1991) Perfluorocarbon-associated gas exchange. Crit Care Med 19:712–722PubMedCrossRefGoogle Scholar
  11. 11.
    Curtis S (1991) Perfluorocarbon-associated gas exchange: a hybrid approach to mechanical ventilation. Crit Care Med 19:600–601PubMedCrossRefGoogle Scholar
  12. 12.
    Greenspan JS, Wolfson MR, Rubinstein SD, Shaffer TH (1990) Liquid ventilation of human preterm neonates. J Pediatr 117:106–111PubMedCrossRefGoogle Scholar
  13. 13.
    Varenne P, Vauron MG (1980) Biological effects of inert gases. Bull Europ Physiopath Resp 16:78–109Google Scholar
  14. 14.
    Barach AL (1936) The therapeutic use of helium. JAMA 16:1273–1280CrossRefGoogle Scholar
  15. 15.
    Kemper KJ, Ritz RH, Benson MS, Bishop MS (1991) Helium-oxygen mixture in the treatment of postextubation stridor in pediatrie trauma patients. Crit Care Med 19:356–359PubMedCrossRefGoogle Scholar
  16. 16.
    Tatsuno K, Imai Y, Konno S (1976) Therapeutic use of helium-oxygen mixture in continuous positive airway pressure of early weaning from mechanical ventilation after cardiovascular surgery in infants. J Thorac Cardiovasc Surg 72:119–122PubMedGoogle Scholar
  17. 17.
    Gruel Y, Bourdelat D, Babut JM (1985) A new method of ventilation with a mixture of helium and oxygen in the management of congenital diaphragmatic hernia. Acta Anesthesiol Belg 3:119–126Google Scholar
  18. 18.
    Wolfson MR, Buthani VK, Shaffer TH, Bowen FW (1984) Mechanics and energetics of breathing helium in infants with bronchopulmonary dysplasia. J Pediatr 104:752–757PubMedCrossRefGoogle Scholar
  19. 19.
    Butt WW, Koren G, England S, et al. (1985) Hypoxia associated with helium-oxygen therapy in neonates. J Pediatr 106:474–477PubMedCrossRefGoogle Scholar
  20. 20.
    Menget A, Burguet A, Fromentin C, Destuynder R (1990) Etude préliminaire sur la ventilation artificielle néonatale par un mélange hélium oxygène. Dixième anniversaire du groupe francophone de réanimation pédiatrique (abstr), Paris, p. 8Google Scholar
  21. 21.
    Slutsky AS (1988) Nonconventional methods of ventilation. Am Rev Respir Dis 138:175–183PubMedCrossRefGoogle Scholar
  22. 22.
    Editorial (1991) High-frequency ventilation. Lancet vol. 337 n° 8743:706–708Google Scholar
  23. 23.
    Mammel MC, Ophoven JP, Lewallen PK, et al. (1991) Acute airway injury during high-frequency jet ventilation and high-frequency oscillatory ventilation. Crit Care Med 19:394–398PubMedCrossRefGoogle Scholar
  24. 24.
    Courtney SE, Weber KR, Spohn WA, et al. (1990) Measurement of tidal volume using a pneumotachometer during high-frequency oscillation. Crit Care Med 18:651–653PubMedCrossRefGoogle Scholar
  25. 25.
    Keszler M, Donn SM, Bucciarelli RL, et al. (1991) Multicenter controlled trial comparing high-frequency jet ventilation and conventional mechanical ventilation in newborn infants with pulmonary interstitial emphysema. J Pediatr 119:85–93PubMedCrossRefGoogle Scholar
  26. 26.
    Sykes MK (1989) High-frequency ventilation. Br J Anaesth 62:475–774PubMedCrossRefGoogle Scholar
  27. 27.
    Bryan AC, Froese AB (1991) Reflections on the HIFI trial. Pediatrics 87:565–567PubMedGoogle Scholar
  28. 28.
    The HIFI study group (1989) High-frequency oscillatory ventilation compared with conventional mechanical ventilation in the treatment of respiratory failure in preterm infants. N Engl J Med 320:88–93CrossRefGoogle Scholar
  29. 29.
    Frantz ID (1990) Newer methods for treatment of respiratory distress. In: Cowett RM, Hay WN Jr (ed): The micropremie: The next frontier. Report of the 99th Ross Conference on pediatrie research. Columbus, Ohio, Ross Laboratories, pp 29–35Google Scholar
  30. 30.
    Abassi S, Bhutani VK, Spitzer AR, Fox WW (1991) Pulmonary mechanics in preterm neon-ates with respiratory failure treated with high-frequency oscillatory ventilation compared with conventional mechanical ventilation. Pediatrics 87:487–493Google Scholar
  31. 31.
    Carlo WA, Siner B, Chatburn RL, et al. (1990) Early randomized intervention with high-frequency jet ventilation in respiratory distress syndrome. J Pediatr 117:765–770PubMedCrossRefGoogle Scholar
  32. 32.
    Clark RH, Gerstmann DR, Null DM Jr, deLemos RA (1990) High-frequency oscillatory ventilation reduces the incidence of severe chronic lung disease in respiratory distress syndrome. Am Rev Respir Dis 141: A687Google Scholar
  33. 33.
    Kinsella JP, Gerstmann DR, Clark RH, et al. (1991) High-frequency oscillatory ventilation versus intermittent mandatory ventilation: Early hemodynamic effects in the premature baboon with hyaline membrane disease. Pediatr Res 29:160–166PubMedCrossRefGoogle Scholar
  34. 34.
    Meredith KS, deLemos RA, Coalson JJ, et al. (1989) Role of lung injury in the pathogenesis of hyaline membrane disease in premature baboons. J Appl Physiol 66:2150PubMedGoogle Scholar
  35. 35.
    Hamm CR, Millian JC, Curtet N, et al. (1990) High-frequency jet ventilation preceded by lung volume recruitment decreases hyaline membrane formation in surfactant deficient lungs. Pediatr Res 27:305AGoogle Scholar
  36. 36.
    Jackson JC, Truog WE, Standaert TA, et al. (1990) High-frequency ventilation reduces alveolar edema in premature monkeys at risk for hyaline membrane disease. FASEB J 4:A945Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • A. Pardou
  • J. M. Bouton

There are no affiliations available

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