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Alterations in Gastrointestinal Barrier Function in Sepsis: The Effect of Lipopolysaccharide on Mucosal Permeability to Hydrophilic Solutes

  • M. P. Fink
Conference paper
Part of the Yearbook of Intensive Care and Emergency Medicine book series (YEARBOOK, volume 1992)

Abstract

Structure and Function of Intestinal Intercellular Tight Junctions The epithelium of the gut serves as a barrier limiting the systemic absorption of intraluminal microbes and microbial products. It has been hypothesized, but certainly not proven conclusively, that derangements in the barrier function of the gut predispose critically ill patients to the development of bacteremia, fungemia, and/ or endotoxemia [1-3].

Keywords

Intestinal Permeability Reactive Oxygen Metabolite Circ Shock Xanthine Dehydrogenase Mucosal Permeability 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • M. P. Fink

There are no affiliations available

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