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Surgical Oncology in Children

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Cancer in Children

Part of the book series: UICC International Union Against Cancer ((1360))

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Abstract

Prior to the advent of chemotherapy and radiation therapy, the management of malignant tumours consisted of radical surgical excision. While this permitted local control, metastatic disease contributed to a poor prognosis. In most childhood cancers the survival rate was under 20%. Radiotherapy was the first effective nonsurgical treatment, used mainly for surgically inaccessible sites or palliatively in advanced disease. Effective multiple-agent chemotherapy was developed initially for the treatment of leukaemia and was later also applied to solid tumours; it is continuing to make an impact on cure and disease-free survival that is greater in children’s cancer than in adults. In addition, more effective chemotherapy and more sophisticated radiotherapy have increased the scope and role of surgery.The realization that chemotherapy, surgery and radiotherapy complement each other has been one of the main reasons for some of the more dramatic improvements in results, probably more so than in the case of the spectacular modern technical innovations in surgery.

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Authors
  1. J. Plaschkes
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  2. B. N. Rao
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Editor information

Editors and Affiliations

  1. Department of Paediatric Oncology, Emma Kinderziekenhuis, Div. of Paediatrics Academic Medical Center, Meibergdreef 9, rm F8-239, 1105 AZ, Amsterdam, The Netherlands

    P. A. Voûte

  2. Department of Radiation Oncology, Beatson Oncology Centre, Western Infirmary, G11 6NT, Glasgow, UK

    Ann Barrett

  3. Service de PĂ©diatrie, Institut Gustave Roussy, Rue Camille Desmoulins, F-94805, Villejuif Cedex, France

    Jean Lemerle

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© 1992 Springer-Verlag Berlin Heidelberg

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Plaschkes, J., Rao, B.N. (1992). Surgical Oncology in Children. In: Voûte, P.A., Barrett, A., Lemerle, J. (eds) Cancer in Children. UICC International Union Against Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84722-6_6

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  • DOI: https://doi.org/10.1007/978-3-642-84722-6_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-84724-0

  • Online ISBN: 978-3-642-84722-6

  • eBook Packages: Springer Book Archive

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