Abstract
Apolipoprotein E (apoE) is a major constituent of chylomicron- and VLDL-remnants. It plays a major role in the clearance of these lipoproteins as it serves as a ligand for recognition by hepatic lipoprotein receptors. With isoelectric focusing (IEF) apoE can be separated into three commonly occuring isoforms e.g. E2, E3 and E4.
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References
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© 1993 Springer-Verlag Berlin Heidelberg
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Havekes, L.M., Mulder, M., de Knijff, P., van den Maagdenberg, A., Frants, R.R. (1993). Rare mutations in the APOE gene associated with dominant mode of inheritance of Familial Dysbetalipoproteinemia (FD). In: Sirtori, C.R., Franceschini, G., Brewer, B.H. (eds) Human Apolipoprotein Mutants III. NATO ASI Series, vol 73. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84634-2_21
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DOI: https://doi.org/10.1007/978-3-642-84634-2_21
Publisher Name: Springer, Berlin, Heidelberg
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