Role of Gangliosides in the Modulation of the Angiogenic Response
The unrestrained growth and metastatic potential of a tumor is strictly correlated to its capacity to induce an efficient capillary network in the host tissue (Folkman J and Cotran R 1976, Ziehe M and Gullino PM, 1982). Under physiological circumstances the ability of a given tissue to produce a neovascular response is under strict controll, i.e. the balance between factors and events favoring or interfering with neovascular growth is in equilibrium.
KeywordsSialic Acid Angiogenic Response Capillary Endothelium Corneal Stroma Microvascular Endothelium
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