Role of Gangliosides in the Modulation of the Angiogenic Response
The unrestrained growth and metastatic potential of a tumor is strictly correlated to its capacity to induce an efficient capillary network in the host tissue (Folkman J and Cotran R 1976, Ziehe M and Gullino PM, 1982). Under physiological circumstances the ability of a given tissue to produce a neovascular response is under strict controll, i.e. the balance between factors and events favoring or interfering with neovascular growth is in equilibrium.
KeywordsProstaglandin Macromolecule PGE1
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