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Malignancies of the Genitourinary Tract pp 237–255Cite as

Management of Early Stages of Testicular Carcinoma: The Current Status

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Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 126))

Abstract

In the last 15 years a dramatic improvement in cure rates for patients with testicular cancer from less than 50% to 90%, has been achieved by the introduction of chemotherapeutic agents such as bleomycin, ifosfamide, cisplatin, and etoposide. It has been demonstrated that patients with minimal tumor load at the time of diagnosis have an excellent survival chance, exceeding 95%. On the basis of these excellent cure rates several clinical trials were performed to investigate whether chemotherapy could be reduced in terms of number of drugs, number of cycles and dosage without affecting the cure rate. At the same time new forms of supportive treatment with third-generation antiemetics and hematopoietic growth factors have improved the tolerability of chemotherapy and reduced the risk of death owing to sepsis.

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Authors and Affiliations

  1. Arbeitsgruppe für Intermedizinische Onkologie, Abteilung für Hematologie/ Onkologie, Medizinische Hochschule Hannover, Konstanty-Gutschow-Strasse 8, W-3000, Hannover 61, Germany

    H.-J. Schmoll

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  1. H.-J. Schmoll
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Editors and Affiliations

  1. Urologische Klinik, Heinrich-Heine-Universität, Moorenstrasse 5, W-4000, Düsseldorf, Germany

    Rolf Ackermann

  2. Medizinische Klinik I, Universität Köln, Joseph-Stelzmann-Strasse 9, W-5000, Köln 41, Germany

    Volker Diehl

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© 1993 Springer-Verlag Berlin Heidelberg

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Schmoll, HJ. (1993). Management of Early Stages of Testicular Carcinoma: The Current Status. In: Ackermann, R., Diehl, V. (eds) Malignancies of the Genitourinary Tract. Recent Results in Cancer Research, vol 126. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84583-3_22

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  • DOI: https://doi.org/10.1007/978-3-642-84583-3_22

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-84585-7

  • Online ISBN: 978-3-642-84583-3

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