Skip to main content

When Should We Stop Intravesical Treatment in Patients with Superficial Bladder Cancer?

  • Conference paper
Malignancies of the Genitourinary Tract

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 126))

  • 41 Accesses

Abstract

Transurethral resection (TUR) is the treatment of choice for patients with superficial bladder cancer (i.e., Ta, T1 tumors). There are few patients in whom cystectomy is indicated as the initial treatment. External beam irradiation or brachytherapy is applied only in special centers. External beam irradiation certainly does not lower the recurrence rate or improve survival compared to TUR [22]. Interstitial radium implants used in a very selected group of patients seem to be highly effective, both in terms of survival and recurrence rate [26].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Bretton PR, Herr HW, Badalament RA. The treatment of superficial transitional cell carcinoma of the bladder with mucosal and/or ductal involvement of the prostatic urethra with intravesical BCG. J Urol 141:853–856

    Google Scholar 

  2. Bretton PR, Herr HW, Kimrnel M, Whitmore WF, Laudone V, Oettgen HF, Fair WR (1990) The response of patients with superficial bladder cancer to a second course of intravesical BCG. J Urol 143:710

    PubMed  CAS  Google Scholar 

  3. Brosman SA (1985) The use of BCG in the therapy of bladder carcinoma in situ. J Urol 134:36

    PubMed  CAS  Google Scholar 

  4. Catalona WJ, Hudson MA, Gillen DP, Andriole GL, Ratliff TL (1987) Risks and benefits of repeated courses of intravesical bacillus Calmette-Guérin theapy for superficial bladder cancer. J Urol 137:220

    PubMed  CAS  Google Scholar 

  5. Dalessio O, Schulman CC, Sylvester R, dePauw M, Robinson M, Denis L, Smith PH, Viggiano G (1983) Prognostic factors in superficial bladder cancer. J Urol 129:730

    Google Scholar 

  6. Fitzpatrick JM, Khan O, Oliver RT, Riddle PR (1979) Longterm follow-up in patients with superficial bladder tumours treated with intravesical Epodyl. Br J Urol 51:545

    Article  PubMed  CAS  Google Scholar 

  7. Flamm J, Havelec L (1990) Factors affecting survival in primary superficial bladder cancer. Eur Urol 17:113

    PubMed  CAS  Google Scholar 

  8. Fossa SD (1985) The need for long term follow-up studies after treatment of superficial bladder cancer, especially after intravesical chemotherapy. In: EORTC Genitiurinary Group monograph 2, part B: superficial bladder tumors. Liss, New York, pp 31–37

    Google Scholar 

  9. Green DF, Robinson MRG, Glashan R, Newling D, Dalesio O, Smith PH (1984) Does intravesical chemotherapy prevent invasive bladder cancer? J Urol 131:33

    PubMed  CAS  Google Scholar 

  10. Heney N, Ahmed S, Flanagan MJ, Frable J, Corder M, Hafermann M, Hawkins I (1983) Superficial bladder cancer: progression and recurrence. J Urol 130:1083

    PubMed  CAS  Google Scholar 

  11. Herr HW, Badalament RA, Amato DA (1989) Superficial bladder cancer treated with BCG: multivariate analysis of factors affecting tumor progression. J Urol 141:22

    PubMed  CAS  Google Scholar 

  12. Herr H, Jakse G, Sheinfeld J (1991) The Tl bladder tumor. J Urol (submitted)

    Google Scholar 

  13. Herr H, Pinsky CM, Whitmore WF (1986) Long-term effect of intravesical bacillus Calmette Guérin on flat carcinoma in situ. J Urol 135:265

    PubMed  CAS  Google Scholar 

  14. Jakse G, Loidl W, Seeber G, Hofstädter F (1984) Stage Tl, grade 3 transitional cell carcinoma of the bladder; an unfavorable tumor. J Urol 137:39

    Google Scholar 

  15. Jakse G (1987) Die Stellung der Zystektomie in der Behandlung des in situ Karzinoms der Harnblase. Akt Urol 18:255

    Article  Google Scholar 

  16. Kavoussi LR, Torrence RJ, Gillen GP, Hudson MA, Haaff EO, Dresner SM, Ratliff TL, Catalona WJ (1988) Results of 6 weekly intravesical bacillus Calmette-Guérin instillations on the treatment of superficial bladder tumors. J Urol 139:935

    PubMed  CAS  Google Scholar 

  17. Koontz W Jr, Heney NM, Soloway MS, Platz C, Hazra TA, Trump DL (1985) Mitomycin C for patients who have failed on thio-tepa. Urology 26 [Suppl 4]: 30–31

    PubMed  Google Scholar 

  18. Kurth K-H, Schroeder FH, Debruyne F, Senge T, Pavone-Macaluso M, de Pauw M, ten Kate F, Sylvester R (1989) Long-term follow-up in superficial transitional cell carcinoma of the bladder: prognostic factors for time to first recurrence, recurrence rate and survival. In: Murphy GP, Khoury S (eds) Therapeutic progress in urological cancer. Liss, New York, pp 481–490

    Google Scholar 

  19. Kurth K-H, Sylvester R, dePauw M, tenKate F (1989) Intracavitary treatment of transitional cell carcinoma of the bladder: questions and lessons after 27 years of experience. Prog Clin Biol Res 310:40

    Google Scholar 

  20. Lutzeyer W. Rübben H, Dahm H (1982) Prognostic parameters in superficial bladder cancer: an analysis of 315 cases. J Urol 127:250

    PubMed  CAS  Google Scholar 

  21. Pagano F, Bassi P, Milam C (1989) Low-dose BCG-Pasteur strain in the treatment of superficial bladder cancer: preliminary results. Prog Clin Biol Res 310:253

    PubMed  CAS  Google Scholar 

  22. Quilty PM, Duncan W (1986) Treatment of superficial tumor of the bladder by radical radiotherapy. Br J Urol 58:147

    Article  PubMed  CAS  Google Scholar 

  23. Rübben H, Lutzeyer W, Fischer N, Deutz F, Lagrange W, Giani G (1988) Natural history and treatment of low and high risk superficial bladder tumors. J Urol 139:283

    PubMed  Google Scholar 

  24. Soloway MS (1988) The management of superficial bladder cancer, with emphasis on intravesical chemotherapy. In: Raghavan D (ed) The management of bladder cancer. Arnold, London

    Google Scholar 

  25. Soloway MS, Ferry A (1987) BCG for treatment of superficial transitional cell carcinoma of the bladder in patients who have failed thiotepa and/or mitomycin C J Urol 137:871

    CAS  Google Scholar 

  26. van der Werft-Messing B, Hop WCJ (1981) Carcinoma of the urinary bladder treated either by radium implant or by transurethral resection only. Int J Radiat Oncol Biol Phys 7:299

    Article  Google Scholar 

  27. Wolf H, Hojgard K (1983) Prognostic factors in local surgical treatment of invasive bladder cancer with special reference to the presence of urothelial dysplasia. Cancer 51:1710

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1993 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

von Heyden, B., Jakse, G. (1993). When Should We Stop Intravesical Treatment in Patients with Superficial Bladder Cancer?. In: Ackermann, R., Diehl, V. (eds) Malignancies of the Genitourinary Tract. Recent Results in Cancer Research, vol 126. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84583-3_12

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-84583-3_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-84585-7

  • Online ISBN: 978-3-642-84583-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics