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Neurotransmitter und psychische Erkrankungen pp 21–27Cite as

Katecholamin-Hypothese

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Part of the book series: Tropon-Symposium VI ((BAYERZNS,volume 6))

Zusammenfassung

Aufgrund der bis heute durchgeführten Studien an depressiven Patienten wissen wir, daß die Katecholamin- bzw. Noradrenalin-Hypothese der Depression in ihrer ursprünglichen Form sich nicht mehr aufrechterhalten läßt. Diese Hypothese führte jedoch zu einer großen Anzahl tierexperimenteller und klinischer Studien, die unser neurobiologisches Wissen um Funktionen und Mechanismen katecholaminerger Neurone wesentlich erweiterten. Trotzdem kennen wir bis heute nicht die biologischen Ursachen eines depressiven Syndroms oder den für die Therapie relevanten Wirkmechanismus von Antidepressiva. Dieses Unwissen ist sicher nicht auf mangelnde Qualität biologisch-psychiatrischer Forschung zurückzuführen. Unsere Kenntnisse über die komplexen, vielfältigen Funktionsabläufe selbst im normalen Hirn sind jedoch auch heute noch so ungenügend, daß es meiner Meinung nach glücklicher Zufälle bedarf, um die neurobiologischen Ursachen eines depressiven Syndroms in absehbarer Zeit eindeutig aufzuklären.

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Authors
  1. N. Matussek
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Editors and Affiliations

  1. Psychiatrische Klinik, Universät Würzburg, Füchleinstr. 15, Würzburg, W-8700, Deutschland

    Helmut Beckmann  & Michael Osterheider  & 

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© 1991 Springer-Verlag Berlin Heidelberg

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Matussek, N. (1991). Katecholamin-Hypothese. In: Beckmann, H., Osterheider, M. (eds) Neurotransmitter und psychische Erkrankungen. Tropon-Symposium VI, vol 6. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84544-4_2

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  • DOI: https://doi.org/10.1007/978-3-642-84544-4_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-54220-9

  • Online ISBN: 978-3-642-84544-4

  • eBook Packages: Springer Book Archive

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