Urate Depositions in Tissues

Conference paper


In histological tissue sections, monosodium urate crystals appear as collections of negative birefringent, needle-like deposits (Fig. 1 a, b). Their electron microscopic equivalent is crystals with a focal parallel arrangement of their long axes (Fig. 1 c, d). Vacuoles inside the crystals are due to the effect of the electron beam (Pritzker et al. 1978). However, the finding of these crystals in histological sections is dependent on several conditions that will be briefly discussed at the end of this chapter.


Synovial Tissue Collagenous Fibril Hyaline Cartilage Gouty Arthritis Urate Crystal 
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© Springer Verlag, Berlin Heidelberg 1991

Authors and Affiliations

  • W. Mohr

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