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Update 1991 pp 153–160Cite as

Gastro-intestinal Mucosal Injury in Shock

  • Conference paper

Part of the book series: Update in Intensive Care and Emergency Medicine ((UICM,volume 14))

Abstract

Blood flow to the splanchnic area is reduced in most forms of shock. In certain forms, such as following cardiac tamponade, the reduction in splanchnic blood flow is disproportionally great while in others, such as sepsis, blood flow rather changes in parallel with cardiac index. The renin-angiotensin axis seems to be important in situations with a disproportionate splanchnic vasoconstriction [1]. Blood flow distribution within the gastro-intestinal tract i.e. the distribution of blood to the various layers of the gut, is changing during ischemia and sepsis to ensure that a larger proportion of flow is directed to the mucosa [2]. Still, shock of various forms as well as regional ischemia of other causes rapidly lead to the development of characteristic injuries of the splanchnic organs. This injury is for the hollow viscera at least initially confined to the superficial layer of the mucosa (Table 1) [3]. This chapter will mainly deal with the pathogenesis and the implications of such injury in the stomach and the small intestine.

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Authors
  1. U. Haglund
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Editor information

Editors and Affiliations

  1. Department of Intensive Care, Erasme Hospital, Free University of Brussels, Route de Lennik 808, B-1070, Brussels, Belgium

    Jean Louis Vincent (Clinical Director) (Clinical Director)

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© 1991 Springer-Verlag Berlin, Heidelberg

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Haglund, U. (1991). Gastro-intestinal Mucosal Injury in Shock. In: Vincent, J.L. (eds) Update 1991. Update in Intensive Care and Emergency Medicine, vol 14. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84423-2_18

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  • DOI: https://doi.org/10.1007/978-3-642-84423-2_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-53672-7

  • Online ISBN: 978-3-642-84423-2

  • eBook Packages: Springer Book Archive

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