Abstract
Septic shock is an acute impairment of tissue perfusion, which is caused by microbes and their products, including endotoxin. The clinical syndrome is characterized by circulatory failure with reduced blood pressure and signs of insufficient perfusion such as oliguria, altered mental status, and increased blood levels of lactate. Hypovolemia due to peripheral pooling of blood and loss of circulating blood volume due to increased capillary permeability is often present in the early phase of septic shock. Restoration of circulating blood volume by fluid resuscitation reveals a hyperdynamic circulation with reduced systemic vascular resistance and normal or high cardiac output [1, 2].
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© 1991 Springer-Verlag Berlin, Heidelberg
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Takala, J., Ruokonen, E. (1991). Blood Flow and Adrenergic Drugs in Septic Shock. In: Vincent, J.L. (eds) Update 1991. Update in Intensive Care and Emergency Medicine, vol 14. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84423-2_17
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DOI: https://doi.org/10.1007/978-3-642-84423-2_17
Publisher Name: Springer, Berlin, Heidelberg
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