The Maternotrophoblastic Interface: Uteroplacental Blood Flow

  • J. Hustin


Soon after implantation, primary trophoblast exerts its proteolytic properties; distended vascular lakes are thus opened, and maternal red blood cells appear within the lacunae at the previllous stage [1]. Knoth and Larsen [2] were surprised to find only one example of such penetration in the ultrastructural study of their 11-day-old implanted ovum. Enders [1], quoting a Carnegie Institute publication by O’Rahilly and Muller, suggests that there is a true blood flow within lacunae of the human placental disk 10–11 days after ovulation, i.e., 4–5 days after implantation. There is now general agreement that the vessels which are tapped are venous capillaries or lakes. It is therefore obvious that only a limited quantity of blood will enter the lacunae through a retrograde effect. Kaufmann [3] has proposed that spiral arteries are tapped around days 28–29. It thus appears that some maternal blood is diverted to the lacunae, but most probably in minute quantities.


Spiral Artery Extravillous Trophoblast Intervillous Space Uteroplacental Blood Flow Primary Trophoblast 
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© Springer-Verlag Berlin Heidelberg 1992

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  • J. Hustin

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