Advertisement

Classification of Abortion Material; Myth or Reality?

Abstract

Pathologists always prefer to examine material within the framework of a classification, and those studying tissues from spontaneous abortions are no exception. Most pathologists usually receive, however, only placental and decidual tissue from cases of abortion, and therefore any classification suitable for widespread application has to be based largely on placental morphology. It is, perhaps, fortuitous that this pragmatic necessity is bolstered by a widespread view that placental changes offer the best basis for classification of abortion material. Any useful classification of abortion material in terms of placental morphology should fulfill two criteria:
  1. 1.

    The classification should be based on simple histological examination of haematoxylin and eosin-stained sections and should not necessitate the use of techniques such as morphometry or electron microscopy.

     
  2. 2.

    There should be a correlation between the types of placental abnormality recognised in the classification and the presumed cause of the abortion.

     

Keywords

Spontaneous Abortion Hydatidiform Mole Placental Villus Decidual Tissue Habitual Abortion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Philippe E, Boué J (1969) Le placenta dans les aberrations chromosomiques léthales. Ann Anat Pathol (Paris) 14: 249–266Google Scholar
  2. 2.
    Philippe E (1973) Morphologie et morphométrie des placentas d’aberration chromosomique létale. Rev Fr Gynecol Obstet 68: 645–649Google Scholar
  3. 3.
    Honore LH, Dill FJ, Poland BJ (1976) Placental morphology in spontaneous human abortions with normal and abnormal karotypes. Teratology 14: 151–166PubMedCrossRefGoogle Scholar
  4. 4.
    Geisler M, Kleinebrecht J (1978) Cytogenetic and histologic analysis of spontaneous abortion. Hum Genet 45: 239–251PubMedCrossRefGoogle Scholar
  5. 5.
    Göcke H, Muradow I, Cremer H (1982) Morphologische und zytogenetische Befunde bei Frühaborten. Verh Dtsch Ges Pathol 66: 141–146PubMedGoogle Scholar
  6. 6.
    Gocke H, Schwanitz G, Muradow I, Zerres K (1985) Pathomorphologie und Genetik in der Frühschwangerschaft. Pathologe 6: 249–259PubMedGoogle Scholar
  7. 7.
    Muntefering H, Dallenbach-Hellweg G, Ratschek M (1988) Pathologische-anatomische Befunde bei der gestörten Frühschwangerschaft. Gynakologe 21: 262–272PubMedGoogle Scholar
  8. 8.
    Rehder H, Coerdt W, Eggers R, Klink F, Schwinger E (1989) Is there a correlation between morphological and cytogenetic findings in placental tissue from early missed abortions? Hum Genet 82: 377–385PubMedCrossRefGoogle Scholar
  9. 9.
    Minguillon C, Eiben B, Bahr-Porsch S, Vogel M, Hansmann H (1989) The predictive value of chorionic villus histology for identifying chromosomally normal and abnormal spontaneous abortions. Hum Genet 82: 373–376PubMedCrossRefGoogle Scholar
  10. 10.
    Novak R, Agamonalis D, Dasu S, Igel H, Platt M, Robinson H, Shehata B (1988) Histological analysis of placental tissue in first trimester abortions. Pediatr Pathol 8: 477–482PubMedCrossRefGoogle Scholar
  11. 11.
    Rockelein G, Schroder J, Ulmer R (1989) Korrelation von Karotyp and Plazentamorphologie beim Frühabort. Pathologe 10: 306–314PubMedGoogle Scholar
  12. 12.
    Rockelein G, Ulmer R, Schwille R (1990) Surface and branching of placental villi in early abortion: relationship to karotype. Virchows Arch [A] 417: 151–158CrossRefGoogle Scholar
  13. 13.
    Rushton DI (1981) Examination of products of conception from previable human pregnancies. J Clin Pathol 34: 819–835PubMedCrossRefGoogle Scholar
  14. 14.
    Rushton DI (1987) Pathology of abortion. In: Fox H (ed) Haines and Taylor: obstetrical and gynaecological pathology, 3rd edn. Livingstone, Edinburgh, pp 1117–1148Google Scholar
  15. 15.
    Rushton DI (1988) Placental pathology in spontaneous miscarriage. In: Beard RW, Sharp F (eds) Early pregnancy loss: mechanisms and treatment. Springer, Berlin Heidelberg New York, pp 149–157CrossRefGoogle Scholar
  16. 16.
    Houwert-de Jong MH (1989) Habitual abortion: views and fact-finding. Thesis, University of UtrechtGoogle Scholar
  17. 17.
    Houwert-de Jong MH, Bruinse HW, Eskes TKAB, Mantingh A, Termijtelen A, Kooyman CD (1990) Early recurrent miscarriage: histology of conception products. Br J Obstet Gynaecol 97: 533–535PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • H. Fox

There are no affiliations available

Personalised recommendations