Abstract
Endoscopic visualization of the embryo (embryoscopy) is a new and evolving technology. The concept of direct visualization of the embryo reflects not only our ongoing quest for improved diagnostic techniques, but also the potential for direct, targeted embryonic therapy. Advancing technology has rendered the fetus and its environment accessible to the “outside” world and, therefore, to diagnosis and therapy. Among the latest of such technologies is embryoscopy, which utilizes high-resolution fiberoptic equipment for direct visualization of the embryo/fetus [1–6].
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Reece EA, Hobbins JC (1991) Embryoscopy: an evolving technology for early prenatal diagnosis. In: Chapman M, Grudzinskas G, Chard T (eds) The embryo normal and abnormal development and growth. Springer, Berlin Heidelberg New York, pp 123–140
Cullen MT, Reece EA, Whetham J, Hobbins JC (1989) Embryoscopy: description and utility of a new technique. Am J Obstet Gynecol 162: 82–86
Cullen MT, Reece EA, Viscarello RR, Hobbins JC (1989) Transcervical endoscopie visualization of prenatally diagnosed anomalies prior to second trimester termination. Proceeding of the Annual Meeting of the Society for Gynecology Investigation, March 1989
Reece EA, Rothmensch S, Whethan J, Cullen M, Hobbins JC (1991) Embryoscopy: a closer look at first-trimester diagnosis and treatment. Am J Obstet Gynecol (submitted)
Westin B (1954) Hysteroscopy in early pregnancy. Lancet ii (267): 872
Galliant A, Lueken RP, Lindermann HJ (1978) New instruments and new methods. A preliminary report about transcervical embryoscopy. Endoscopy 10: 47
Donald I, MacVicar J, Brown TG (1958) Investigation of abdominal masses by pulsed ultrasound. Lancet ii (274): 1188–1194
Hon EH, Quilligan EJ (1967) The classification of fetal heart rate. Conn Med 31: 779
Green JJ, Hobbins JC (1988) Abdominal ultrasound of the first trimester fetus. Am J Obstet Gynecol 159: 165
Hon EH (1968) An atlas of fetal heart rate patterns. Harty, New Haven
Manning FA, Hill LM, Platt LD (1981) Qualitative amniotic fluid volume determination by ultrasound: antepartum detection of intrauterine growth retardation. Am J Obstet Gynecol 139: 254
Patrick J, Campbell K, Carmichael L, Natale R, Richardson B (1982) Patterns of gross fetal body movements over 24 hour observation intervals during the last 10 weeks of pregnancy. Am J Obstet Gynecol 142: 363–371
Manning FA, Lange FR, Morrison J, Harman CR (1983) Determination of fetal health: methods for antepartum and intrapartum fetal assessment. Curr Probl Obstet Gynecol 7: 1
Beard RW, Filshie GM, Knight CA, Roberts GM (1979) The significance of the changes in the continuous fetal heart rates in the first stage of labor. J Obstet Gynecol Br Commonw 78: 865
Romero R, Pilu G, Jeanty P, Ghidini A, Hobbins JC (1988) Prenatal diagnosis of congenital anomalies. Appleton and Lange Norwalk
Golbus MS, McGonigle KF, Goldberg JD, Filly RA, Callen PW, Anderson RL (1989) Fatal tissue sampling. The San Francisco experience with 190 pregnancies. West J Med 150: 423–430
Valenti C (1972) Endoamnioscopy and fetal biopsy. A new technique. Am J Obstet Gynecol 141: 561–564
Scrimgeour JB (1973) Other techniques for antenatal diagnosis. In: Emery AEH (ed) Antenatal diagnosis of genetic disease. New York: Churchill-Livingstone, New York, pp 40–57
Hobbins JC, Mahoney MJ (1974) In utero diagnosis of hemoglobinopathies. Technique for obtaining fetal blood. N Engl J Med 290: 1065–1067
Rodeck CH, Nicolaides KH (1986) Fetoscopy. Br Med Bull 42: 296–300
Mahoney MJ, Hobbins JC (1977) Prenatal diagnosis of chondroectoderman dysplasia ( Ellis-Van Creveld syndrome) with fetoscopy and ultrasound. N Engl J Med 297: 258
Elias S (1983) Fetoscopy in prenatal diagnosis. Clin Perinatol 10: 357–367
Hobbins JC, Mahoney MJ (1974) Progress toward in utero diagnosis of hemoglobinopathies: technique for obtaining fetal blood. N Engl J Med 290: 10651067
Daffos F, Capella-Pavlovsky M, Forestier F (1985) Fetal blood sampling during pregnancy with use of a needle guided by ultrasound. A study of 606 consecutive cases. Am J Obstet Gynecol 153: 655–660
Hobbins JC, Grannum P, Romero R, Reece EA (1985) Percutaneous umbilical blood sampling. Am J Obstet Gynecol 152: 1–6
Sievers S, Hagenbusch M, Eckert M (1983) Management of pregnant women with thalassemia minor. Fortschr Med 101: 687–688
Hogge WA, Schomberg SA, Golbus MS (1986) Chorionic villus sampling: experience of the first 1000 cases. Am J Obstet Gynecol 154: 2349
Martin AO, Simpson JL, Rosinsky B et al. (1986) Chorionic Villus sampling in continuing pregnancies. II. Cytogenetic Reliability. Am J Obstet Gynecol 154: 1353
Hobbins JC, Grannum PAT, Berkowitz RL et al. (1979) Ultrasound in the diagnosis of congenital anomalies. Am J Obstet Gynecol 134: 331
Bulic M, Podobnik M et al. (1987) First trimester diagnosis of low obstructive uropathy. An indication of initial renal function of the fetus. J Clin Ultrasound 6: 715
Vergani P, Ghidini A et al. (1987) Antenatal diagnosis of fetal acrania. J Ultrasound Med 6: 715
Hill LM, Thomas ML et al. (1988) Sonographic assessment of the first trimester fetus. A cautionary note. Am J Perinatol 7: 97
Cutis JA, Watson L (1988) Sonographic diagnosis of omphalocele in the first trimester of fetal gestation. J Ultrasound Med 7: 97
Timor-Tritsch IE, Warner WB, Peisner DB, Pirsone E (1989) First trimester midgut herniation. A high frequency transvaginal sonographic study. Am J Obstet Gynecol 161: 831–833
Dumez Y (1990) Embryoscopy and congenital malformations. Proceedings of International Conference on Chorionic Villus Sampling and Early Prenatal Diagnosis, 28–29 May 1990, Athens
Roume J, Aubry MC, Labbe F, Dumez Y, Aubry JP, Henrion R (1985) Prenatal diagnosis of limb and digital abnormalities. Evaluation of the activity of the Port Royal University Clinic from 1979 to 1983. J Genet Hum 33: 457–461
Dumez Y (1988) Embryoscopy and congenital malformations. Proceedings of the International Conference on Chorionic Villous Sampling and Early Prenatal Diagnosis, 28–29 May 1988, Athens
Moore KL (1988) The developing human. Clinically oriented embryology, 4th edn. Saunders, Philadelphia
Arey LB (1974) Development anatomy, 7th rev edn Saunders, Philadelphia
Hamilton WJ, Boyd JD, Mossman HW (1964) Human embryology, 3rd edn. Heffner, Cambridge
Pinter E, Reece EA, Leranth CZ, Sanyal MK, Hobbins JC, Mahoney MJ, Naftolin F (1986) Yolk sac failure in embryopathy due to hyperglycemia. An ultrastructural analysis of the yolk sac differentiation associated with embryopathy in rat conceptuses under hyperglycemic conditions. Teratology 33: 363–374
Reece EA, Pinter E, Leranth CZ, Sanyal MK, Hobbins JC, Mahoney MJ, Naftolin F (1985) Ultrastructural analysis of malformations of the embryonic neural axis induced by hyperglycemic conceptus culture. Teratology 32: 363–374
Reece EA, Pinter E, Leranth CZ, Garcia-Segura LM, Sanyal MK, Hobbins JC, Mahoney MJ, Naftolin F (1989) Yolk sac failure in embryopathy due to hyperglycemia: horseradish peroxidase uptake in the assessment of yolk sac dysfunction. Ostet Gynecol 74: 755–762
Reece EA, Hobbins JC (1986) Diabetic embryopathy: pathogenesis, prenatal diagnosis and prevention. Obstet Gynecol Sury 41: 325–335
Reece EA, Scioscia AL, Pinter E, Hobbins JC, Green JJ, Leranth CZ, Mahoney MJ, Naftolin F (1988) Prognostic significance of the human yolk sac assessed by ultrasonography. Am J Obstet Gynecol 159: 1191–1194
Anderson WF (1984) Prospects for human gene therapy. Science 226: 401
Reece EA, Pinter E, Leranth CZ, Sanyal MK, Hobbins JC, Mahoney MJ, Naftolin F (1985) Ultrastructural analysis of malformations of the embryonic neural axis induced by hyperglycemic conceptus culture. Teratology 32: 363–374
Anderson WF (1985) Human gene therapy: scientific and ethical considerations. J Med Philos 10: 275
Kantoff PW, Gillis AP, McLachlin OR et al. (1987) Expression of human adenosine deaminase in nonhuman primates after retrovirus-mediated gene transfer. J Exp Med 166: 219–234
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1992 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Reece, E.A. (1992). Embryoscopy. In: Barnea, E.R., Hustin, J., Jauniaux, E. (eds) The First Twelve Weeks of Gestation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84385-3_22
Download citation
DOI: https://doi.org/10.1007/978-3-642-84385-3_22
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-84387-7
Online ISBN: 978-3-642-84385-3
eBook Packages: Springer Book Archive