Hydatidiform Mole and Related Disorders

  • T. Maruo
  • M. Mochizuki

Abstract

“Hydatidiform mole” basically means a fluid-filled cystic mass, it is derived from the Greek word hydatis meaning a drop of water, and the Latin word moles meaning a mass. A classic hydatidiform mole is an abnormal conceptus without an embryo, with gross hydropic swelling of the placental villi and usually pronounced trophoblastic proliferation of both cytotrophoblastic and syncytial elements. The villous swelling leads to central cistern formation with a concomitant compression of the connective tissue that has lost its vascularity. Microscopically there is complete villous hydrops, absence of chorionic blood vessels, and a variable degree of trophoblastic hyperplasia. The hydrops might be caused by hyperplasia or dysplasia of the trophoblast, leading to oversecretion of fluid into the villous stroma. This may explain the mechanism in molar change. When there is a failure of the villous vessels to link up with those of the embryo, partial hydatidiform mole may develop in the presence of an embryo.

Keywords

Progesterone Estradiol Proteinuria Perforation Liquefaction 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • T. Maruo
  • M. Mochizuki

There are no affiliations available

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