Skip to main content
SpringerLink
Log in
Book cover

Supplementum X, 41. Jahrgang 1990 Verhandlungen der Deutschen Dermatologischen Gesellschaft pp 81–83Cite as

Heutiger Stand der histologischen und immunhistochemischen Diagnostik des malignen Melanoms

  • Conference paper

  • 38 Accesses

Part of the book series: Der Hautarzt ((VDGDERMATOLOGIE,volume 36))

Zusammenfassung

Die histologische Diagnose und Differentialdiagnose des malignen Melanoms der Haut gehört zu den schwierigsten Problemen in der Derma topathologie. Die entscheidende Basis für eine exakte Melanom-Diagnose liegt in der systematischen Formulierung zuverlässiger und reproduzierbarer Kriterien [1,9]. Ohne diese Kriterien drängt sich ein Vergleich mit den beiden Werken von L. Pirandello, „Man Weiß Nicht Wie” oder „So Ist Es Wie Es Ihnen Scheint” auf. Die wichtigsten Parameter für die Diagnose eines malignen Melanoms sind in Tabelle 1 zusammengefaßt.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   54.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Literatur

  1. Ackerman AB (1980) Malignant melanoma: a unifying concept. Human Pathol 11:59–595

    Google Scholar 

  2. Bröcker EB, Suter L, Brüggen J, Ruiter DJ, Macher E, Sorg C (1985) Phenotypic dynamics of tumor progression in human malignant melanoma. Int J Cancer 36: 29–35

    Article  PubMed  Google Scholar 

  3. Bröcker EB, Zwadlo G, Holzmann B, Macher E, Sorg C (1988) Inflammatory cell infiltrates in human melanoma at different stages of tumor progression. Int J Cancer 41:562– 567

    Google Scholar 

  4. Clark WH Jr, Eider DE, Guerry IV DP, Braitman LE, Trock BJ, Schultz D, Synnestvedt M, Halpern AC (1989) Model predicting survival in stage I melanoma based on tumor progression. J Natl Cancer Inst 81: 1893–1904

    Article  PubMed  Google Scholar 

  5. Cochran AJ, Wen D-R, Herschman HR (1984) Occult melanoma in lymph nodes detected by antiserum to S-100 protein. Int J Cancer 34: 159–163

    Article  PubMed  CAS  Google Scholar 

  6. Flügge G, Rassner G (1989) Darstellung von S-100-Protein in malignen Melanomen der Haut. Hautarzt 40: 290–295

    PubMed  Google Scholar 

  7. Kath R, Rodeck U, Menssen HD, Mancianti M-L, Linnenbach AJ, Eider DE, Herlyn M (1989) Tumor progression in the human melanocytic system Anticancer Res 9: 865–872

    CAS  Google Scholar 

  8. Kaufmann R, Weber L, Klein CE (1990) Integrine–neue Rezeptormoleküle: ihre Bedeutung für die Differenzierung, Regeneration und Immunantwort der Haut. Hautarzt 41: 256–261

    Google Scholar 

  9. Kerl H, Hödl S, Kresbach H, Stettner H (1982) Diagnosis and prognosis of the early stages of cutaneous malignant melanoma. In: Burghardt E, Holzer E (eds) Clinics in oncology, vol 1. Saunders, London, pp 433–453

    Google Scholar 

  10. MacKie RM, White SI, Seywright MM, Young H (1989) An assessment of the value of Ag NOR staining in the identification of dysplastic and other borderline melanocytic naevi. Br J Dermatol 120: 511–516

    Article  PubMed  CAS  Google Scholar 

  11. 11.Miettinen M, Franssila K (1989) Immunohistochemical spectrum of malignant melanoma. Lab Invest 61: 623–628

    Google Scholar 

  12. Moretti S, Massobrio R, Brogelli L, Novelli M, Giannotti B, Bernengo MG (1990) Ki67 antigen expression correlates with tumor progression and HLA-DR antigen expression in melanocytic lesions. J Invest Dermatol 95: 320–324

    Article  PubMed  CAS  Google Scholar 

  13. Smolle J, Soyer HP, Kerl H (1989) Proliferative activity of cutaneous melanocytic tumors defined by Ki-67 monoclonal antibody. Am J Dermatopathol 11: 301–307

    Article  PubMed  CAS  Google Scholar 

  14. Soyer HP, Smolle J, Torne R, Kerl H (1987) Transferrin receptor expression in normal skin and in various cutaneous tumors. J Cut Pathol 14: 1–5

    Article  CAS  Google Scholar 

  15. van Muijen GNP, Ruiter DJ, Hoefakker S, Johnson JP (1990) Monoclonal antibody PAL-Ml recognizes the transferrin receptor and is a progression marker in melanocytic lesions. J Invest Dermatol 95: 65–69

    Article  PubMed  Google Scholar 

  16. Wiek MR, Swanson PE, Rocamora A (1988) Recognition of malignant melanoma by monoclonal antibody HMB-45. An immunohistochemical study of 200 paraffinembedded cutaneous tumors. J Cut Pathol 15: 201–207

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Univ.-Klinik für Dermatologie, und Venerologie in Graz, Auenbruggerplatz 8, A-8036, Graz, Germany

    Univ.-Prof. Dr. Helmut Kerl, J. Smolle, L. Ci Rroni, H. P. Soyer & S. Hödl

Authors
  1. Univ.-Prof. Dr. Helmut Kerl
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. Smolle
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. L. Ci Rroni
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. H. P. Soyer
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. S. Hödl
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Hautklinik Linden, Medizinische Hochschule Hannover, Ricklinger Straße 5, D-3000, Hannover 91, Germany

    Sandor Marghescu , Dietrich Lubach  & Christine Neumann ,  & 

Rights and permissions

Reprints and permissions

Copyright information

© 1991 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Kerl, H., Smolle, J., Rroni, L.C., Soyer, H.P., Hödl, S. (1991). Heutiger Stand der histologischen und immunhistochemischen Diagnostik des malignen Melanoms. In: Marghescu, S., Lubach, D., Neumann, C. (eds) Supplementum X, 41. Jahrgang 1990 Verhandlungen der Deutschen Dermatologischen Gesellschaft. Der Hautarzt, vol 36. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84370-9_27

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-84370-9_27

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-53468-6

  • Online ISBN: 978-3-642-84370-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation