Modulation of Endothelial Cell Function by Hypoxia: Perturbation of Barrier and Anticoagulant Function, and Induction of a Novel Procoagulant Activity
Regulation of vascular permeability and the coagulation mechanism are two central properties of the endothelium (Gimbrone 1986). The presence of multiple active mechanisms through which endothelial cells contribute to the maintenance of barrier function and fluidity of blood has been demonstrated, suggesting that endothelial regulation of vascular homeostasis occurs in response to environmental stimuli.
KeywordsTissue Factor Procoagulant Activity Bovine Aortic Endothelial Cell Endothelial Monolayer Endothelial Cell Surface
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