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Correlated Activity of Neurons: A Neural Code for Higher Brain Functions?

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Part of the book series: Springer Series in Synergetics ((SSSYN,volume 49))

Abstract

This chapter describes some response properties of single neurons and the interactions between them in both a sensory area (the auditory cortex) and an “association” area (the frontal cortex) of the monkey. The data described were obtained by simultaneous recording of several (6–10) neurons by six microelectrodes, in behaving animals.

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References

  • Abeles, M. (1981): The role of the cortical neuron: Integrator or coincidence detector. Isr. J. Med. Sci. 18, 83–92

    Google Scholar 

  • Abeles, M. (1982): Local cortical circuits: an electrophysiological study. Studies of brain function. Vol. 7 (Springer, Berlin, Heidelberg)

    Google Scholar 

  • Abeles, M. (1983): The quantification and graphic display of correlations among three spike trains. IEEE Trans. Biomed. Eng. BME 30, 236–239

    Article  Google Scholar 

  • Abeles, M. (1991) Corticonics: Neural circuits of the Cerebral Cortex. Cambridge University Press, Cambridge

    Book  Google Scholar 

  • Abeles, M., Goldstein, M.H. (1977) Multiple spike train analysis. Proc. IEEE 65, 762–773

    Article  Google Scholar 

  • Abeles, M., Gerstein, G.L. (1988): Detecting spatiotemporal firing patterns among simultaneously recorded single neurons. J. Neurophysiol. 60, 909–923

    Google Scholar 

  • Abeles, M., Assaf, J., Gottlieb, Y., Hodis, H., Vaadia, E. (1975) Speculation on a neural substrate for immediate memory. Sensory Physiology and Behavior 15, 117–126

    Google Scholar 

  • Abeles, M., de Ribaupierre, F., de Ribaupierre, E. (1983): Detection of single unit responses which are loosely time-locked to a stimulus. IEEE Trans. Syst. Man. Cyber. SMC 13, 683–691

    Google Scholar 

  • Aertsen, A.M.H.J., Gerstein, G.L. (1985): Evaluation of neuronal connectivity: sensitivity of cross-correlation. Brain Res. 340, 341–354

    Article  Google Scholar 

  • Aertsen, A.M.H.J., Gerstein, G.L., Habib, M.K., Palm, G. (with the collaboration of P. Gochin and J. Kruger) (1989) Dynamics of neuronal firing correlation: modulation of “effective connectivity”. J. Neurophysiol. 61, 900–917

    Google Scholar 

  • Allum, J.H.J., Hepp-Reymond, M.C., Gysin, R. (1982): Cross-correlation analysis of interneuronal connectivity in the motor cortex of the monkey. Brain Res. 231, 325–334

    Article  Google Scholar 

  • Amit, D.J. (1987) The properties of models of simple neural networks. Heidelberg Colloquium on Glassy Dynamics. van Hemmen J.L. and Morgenstern I. (eds.), Springer, Heidelberg

    Google Scholar 

  • Barlow, H.B. (1972): Single units and sensation: A neuron doctrine for percepteral psychology. Perception 1, 371–394

    Article  Google Scholar 

  • Braitenberg, V. (1978): Cell assemblies in the cerebral cortex. Theoretical Approaches to Complex Systems. Lecture Notes in Biomathematics. Ed. by Heim R, Palm G (Springer, Berlin, Heidelberg) Vol. 21, 171–188

    Google Scholar 

  • Burns, D.B., Webb, A.C. (1979): The correlation between discharge times of neighboring neurons in isolated cerebral cortex. Proc. Roy. Soc. London B 203, 347–360

    Article  ADS  Google Scholar 

  • Butters, N., Pandya, D. (1969): Retention of delayed alternation: Effect of selective lesions of sulcus principalis. Science 165, 1271–1273

    Article  ADS  Google Scholar 

  • Dayhoff, J.E., Gerstein, G.L. (1983): Favoured patterns in spike trains. II. Application. J. Neurophysiol. 49, 1349–1363

    Google Scholar 

  • Deecke, L., Kornhuber, H.H., Lang, W., Lang, M., Schreiber, H. (1985): Timing function of the frontal cortex in sequential motor cortex in motor and learning tasks. Human Neurobiol. 4, 143–154

    Google Scholar 

  • Dickson, J.W., Gerstein, G.L. (1974): Interactions between neurons in auditory cortex of the cat. J. Neurophysiol. 37, 1239–1261

    Google Scholar 

  • Donchin, E. (ed.) (1984): Cognitive Psychophysiology. The Carmal Conferences. Vol. 1 ( Erlbaum, New Jersey )

    Google Scholar 

  • Eckhorn, R., Bauer, R., Jordan, W., Brosch, M., Kruse, W., Munk, M., Reitboeck, H.J. (1988): Coherent oscillations: A mechanism of feature linking in the visual cortex? Biol. Cybern. 60(2), 121–30

    Article  Google Scholar 

  • Edelman, G.M. (1981): Group selection as the basis for higher brain function. The organization of the cerebral cortex. Proceedings of a neuroscience research program colloquium. Ed. by Schmitt et al. ( MIT Press, Cambridge ) pp. 536–563

    Google Scholar 

  • Evarts, E.V., Shinoda, Y., Wise, S.P. (1984): Neurophysiological approach to higher brain function. ( Wiley, New York )

    Google Scholar 

  • Fetz, E.E., Gustafson, B. (1983): Relation between shapes of post-synaptic potentials and changes in firing probability of cat motoneuron. J. Physiol. (Lond.) 341, 387–410

    Google Scholar 

  • Frostig, R., Gottlieb, Y., Vaadia, E., Abeles, M. (1983): The effects of stimuli on the activity and functional connectivity of local neuronal groups in the cat auditory cortex. Brain Res. 272, 211–221

    Article  Google Scholar 

  • Fuster, J.M. (1980): The Prefrontal Cortex. Raven Press, New York

    Google Scholar 

  • Gassanov, U.G., Galashina, A.G., Bogdanov, A.V. (1980): A study of neuron systems activity in learning. In Neural Mechanisms of Goal-Directed Behavior and Learninged. by Thompson, R.F. et al. (Academic, New York ) pp. 341–352

    Google Scholar 

  • Gazanov, U.G., Galashina, A.G., Bogdanov, A.V. (1980) A study of neuron systems activity in learning. Neural Mechanisms of Goal-Directed Behavior and Learning 341–352

    Google Scholar 

  • Gerstein, G.L. (1988): Information flow and state in cortical neural networks: Interpreting multi-neuron experiments. In Organization of Neural Networks, Ed. by von Seelen W. et al. ( VCH, Weinheim ) pp. 53–85

    Google Scholar 

  • Gerstein, G.L., Aertsen, A.M.H.J. (1985): Representation of cooperative firing activity among simultaneously recorded neurons. J. Neurophysiol. 54, 1513–1526

    Google Scholar 

  • Gerstein, G.L., Perkel, D.H, Dayhoff, J.E. (1985): Cooperative firing activity in simultaneously recorded populations of neurons: detection and measurement. J. Neuroscience. 5, 881–889

    Google Scholar 

  • Goldberg, M.E., Segraves, M.A. (1987): Visuospatial and motor attention in the monkey. Neuropsychologia 25, 107–118

    Article  Google Scholar 

  • Goldman, P.S., Nauta, W.J.H. (1977): Columnar distribution of cortico-cortical fibers in the frontal association, limbic and motor cortex of the developing Rhesus monkey. Brain Res. 122, 393–413

    Article  Google Scholar 

  • Goldman-Rakic, P.S. (1987): Circuitry of primate prefrontal cortex and the regulation of behavior by representational knowledge. Mountcastle VB, Plum F (eds) The Nervous System, Vol. V, Handbook of Physiology, Am. Physiol. Soc., Bethesda, MD, pp. 373–417

    Google Scholar 

  • Gottlieb, Y., Vaadia, E., Abeles, M. (1989): Single unit activity in the auditory cortex of a monkey performing a short term memory to tones task. Exp. Brain Res. 74, 139–148

    Google Scholar 

  • Gray, C.M., Singer, W. (1989) Stimulus-specific neuronal oscillations in orientation columns of cat visual cortex. Proc. Natl. Acad. Sci. USA, 86, 1698–1702

    Article  ADS  Google Scholar 

  • Hebb, D.O. (1949): The organization of behavior: a neuropsychological theory( Wiley, New York )

    Google Scholar 

  • Hopfield, J.J. (1982): Neuronal networks and physical systems with emergent collective computational abilities. Proc. Natl. Acad. Sci. USA, 79, 2554–2556

    Article  ADS  MathSciNet  Google Scholar 

  • Hopfield, J.J., Tank, D.W. (1986): Computing with neural circuits: A model. Science 233, 625–633

    Article  ADS  Google Scholar 

  • Kirkwood, P.A., Sears, T.A. (1982): The effect of single afferent impulses on the probability of firing of external intercostal motoneurons in the cat. J. Physiol. 322, 315–336

    Google Scholar 

  • Kruger, J. (1983): Simultaneous individual recordings from many cerebral neurons: Techniques and results. Rev. Physiol. Biochem. Pharmacol. 98, 177–233

    Article  Google Scholar 

  • Kruger, J., Aiple, F. (1988): Multimicroelectrode investigation of monkey striate cortex: spike trains correlations in infragranular layers. J. Neurophysiol. 60, 798–828

    Google Scholar 

  • Levick, W.R., Cleland, B.G., Dubin, M.W. (1972): Lateral geniculate neurons of cat: Retinal inputs and physiology. Investigative Ophthalmology 1, 302–310

    Google Scholar 

  • Lindsey, B.G., Gerstein, G.L. (1979): Interactions among an ensemble of chordotonal organ receptors and motor neurons of the crayfish claw. J. Neurophysiol. 42, 383–399

    Google Scholar 

  • Lurito, J.T., Schwartz, A.B., Petrides, M., Kettner, R.E., Georgopoulos, A.P. (1988): Cross-correlations between motor cortical cells simultaneously recorded during reaching task in the monkey. Soc. Neurose. Abst. 14, 142. 5

    Google Scholar 

  • McNaughton, B.L., O’Keefe, J., Barnes, C.A. (1983): The stereotrode: A new technique for simultaneous isolation of several single units in the central nervous system from multiple unit records. J. Neurosci. Methods 8, 391–397

    Article  Google Scholar 

  • Moore, G.P., Perkel, D.H., Segundo, J.P. (1966): Statistical analysis and functional interpretation of neuronal spike data. Ann. Rev. Physiol. 28, 493–522

    Article  Google Scholar 

  • Moore, G.P., Segundo, J.P., Perkel, D.H., Levitan, H. (1970): Statistical signs of synaptic interactions in neurons. Biophysical J. 10, 876–900

    Article  ADS  Google Scholar 

  • Murphy, J.T., Kwan, H.C., Wong, Y.C. (1985): Cross-correlation studies in primate motor cortex: Synaptic interaction and shared input. Can J Neurol. Sci. 12, 11–23

    Google Scholar 

  • Niki, H., Watanabe, M. (1976): Pre-frontal unit activity and delayed response: Relation to cue location versus direction of response. Brain Res. 105, 79–88

    Article  Google Scholar 

  • Niki, H., Watanabe, M. (1979): Prefrontal and cingulate unit activity during timing behavior in the monkey. Brain Res. 171, 213–224

    Article  Google Scholar 

  • Palm, G. (1982): Neural assemblies, an alternative approach to artificial intelligence. Studies of Brain Function, Vol. 7 (Springer, Berlin, Heidelberg)

    Google Scholar 

  • Passingham, R.E. (1975): Delayed matching after selective prefrontal lesions in monkeys (macaca mulatta). Brain Res. 92, 89–102

    Article  Google Scholar 

  • Perkel, D.H., Gerstein, G.L., Moore, G.P., (1967): Neuronal spike trains and stochastic point processes: II. Simultaneous spike trains. Biophys. J. 7, 419–440

    Article  Google Scholar 

  • Perrett, D.I., Rolls, E.T., Caan, W. (1982): Visual neurons responsive to faces in monkey temporal cortex. Exp. Brain Res. 47, 329–342

    Article  Google Scholar 

  • Petrides, M. (1986): The effect of periarcuate lesions in the monkey on performance of symmetrically and asymmetrically reinforced and auditory go, no-go tasks. J. Neurosci. 6, 2054–2063

    Google Scholar 

  • Rumelhart, D.E., Hinton, G.E., Williams, R.J. (1986): Learning internal ed. representation by error propagation. In Parallel Distributed Processing, ed. by Rumelhart DE et al. ( MIT Press, Cambridge )

    Google Scholar 

  • Sompolinsky, H. (1987): The theory of neural networks: the Hebb rule and beyond. Heidelberg Colloquium on Glassy Dynamics, ed. by van Hemmen JL and Morgenstern, I. (Springer, Berlin, Heidelberg. )

    Google Scholar 

  • Tam, D.C., Ebner, T.J., Knox, C.K. (1988): Conditional cross-interval correlation analyses with applications to simultaneously recorded cerebellar Purkinje neurons. J. Neurosci. Methods 23, 23–33

    Article  Google Scholar 

  • Toyama, K., Kimura, M., Tanaka, K. (1981): Crosscorrelation analysis of interneuronal connectivity in cat visual cortex. J. Neurophysiol. 46, 191–201

    Google Scholar 

  • Tso, D., Gilbert, C.D., Wiesel, T. (1986): Relationships between horizontal architecture in cat striate cortex as revealed by cross-correlation analysis. J. Neurosci. 6, 1160–1170

    Google Scholar 

  • Vaadia, E., Abeles, M. (1987): Temporal firing patterns of single units, pairs and triplets of units in the auditory cortex. J. Isr. Med. Sci. 23, 75–83

    Google Scholar 

  • Vaadia, E., Gottlieb, H., Abeles, M. (1982): Single unit activity related to sensorimotor association in auditory cortex of a monkey. J. Neurophysiol. 48, 201–213

    Google Scholar 

  • Vaadia, E., Benson, D.A., Goldstein, M.H., Hienz, R.D. (1986): Unit study of monkey frontal cortex: Active localization of auditory and visual stimuli. J. Neurophysiol. 56, 934–952

    Google Scholar 

  • Vaadia, E., Kurata, K., Wise, S.P. (1988): Neuronal activity preceding directional and nondirectional cues in the premotor cortex of Rhesus monkeys. Somatosensory Res. 6, 207–230

    Article  Google Scholar 

  • Vaadia, E., Bergman, H., Abeles, M. (1989): Neuronal activities related to higher brain functions — Theoretical and experimental implications. IEEE Trans. Biomed. Eng. 36, 25–35

    Article  Google Scholar 

  • Watanabe, M. (1986): Prefrontal unit activity during delayed conditional Go/NoGo discrimination in Monkey I. Relation to stimulus. Brain Res. 382, 1–14

    Article  Google Scholar 

  • Wise, S.P., Mauritz, K.H. (1985): Set related neuronal activity in the premotor cortex of rhesus monkeys: effects of changes in motor set. Proc. R. Soc. Lond. B 223, 331–354

    Article  ADS  Google Scholar 

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Vaadia, E., Ahissar, E., Bergman, H., Lavner, Y. (1991). Correlated Activity of Neurons: A Neural Code for Higher Brain Functions?. In: Krüger, J. (eds) Neuronal Cooperativity. Springer Series in Synergetics, vol 49. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84301-3_11

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  • DOI: https://doi.org/10.1007/978-3-642-84301-3_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-84303-7

  • Online ISBN: 978-3-642-84301-3

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