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Prader-Willi Syndrome pp 1–11Cite as

Introduction and Overview of Prader-Willi Syndrome

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Part of the book series: NATO ASI Series ((ASIH,volume 61))

Abstract

In 1680, a painter to the Spanish court of King Charles II, Juan Carreno de Miranda, immortalized on canvas a six year old obese girl who was known for her “feeblemindedness” and “bad temper”. She has almond-shaped palpebral fissures, a down-turned mouth, small hands, and central obesity, all characteristic of Prader-Willi Syndrome. She hangs in the Prado Museum in Madrid, clad in one painting, nude in the other, a testimony to the fact that the condition we now know as Prader-Willi Syndrome has existed for centuries. But it was not until 1956 that Drs. Prader, Labhart and Willi first described the pattern of abnormalities which includes low muscle tone, incomplete sexual development, obesity, and mental handicap (Prader et al, 1956) and which now bears their names.

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Author information

Authors and Affiliations

  1. Section of Genetics/Dysmorphology, Department of Pediatrics and Steele Memorial Children’s Research Center, University of Arizona College of Medicine, Tucson, Arizona, USA

    Suzanne B. Cassidy (M.D.)

Authors
  1. Suzanne B. Cassidy
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Editor information

Editors and Affiliations

  1. College of Medicine, Section of Genetics/Dysmorphology, University of Arizona, Tucson, Arizona, 85724, USA

    Suzanne B. Cassidy

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© 1992 Springer-Verlag Berlin Heidelberg

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Cassidy, S.B. (1992). Introduction and Overview of Prader-Willi Syndrome. In: Cassidy, S.B. (eds) Prader-Willi Syndrome. NATO ASI Series, vol 61. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84283-2_1

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  • DOI: https://doi.org/10.1007/978-3-642-84283-2_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-84285-6

  • Online ISBN: 978-3-642-84283-2

  • eBook Packages: Springer Book Archive

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