Skip to main content

Pharmakologische Grundlage der ‚Therapieresistenz‘ bei der Behandlung mit Antidepressiva

  • Conference paper

Part of the book series: Tropon-Symposium ((BAYERZNS,volume 5))

Zusammenfassung

Die Therapie-Resistenz auf die Behandlung mit Antidepressiva ist ein Problem, mit welchem praktizierende Ärzte in zunehmendem Maße konfrontiert sind. Immerhin sprechen ca. 30%-35% der depressiven Patienten ungenügend oder gar nicht auf eine pharmakologische Behandlung an.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   54.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Åsberg M, Bertilsson L (1979) Serotonin in depressive illness. In: Saletu B, Berner P, Hollister LE (Hrsg) Studies of CSF 5-HIAA in Neuropsychopharmacology. Pergamon Press, New York, pp 105–115

    Google Scholar 

  • Banki CM, Molnar G, Vojnik M (1981) Cerebrospinal fluid amine metabolites, tryptophane and clinical parameters in depression. J Affect Dis 3:91–99

    Article  PubMed  CAS  Google Scholar 

  • Carlsson A et al. (1969) Effect of antidepressant drugs on the depletion of intraneuronal brain 5-hydroxytryptamine stores caused by 4-methyl-α-ethyl-meta-tyramine. Eur J Pharmacol 5:357–366

    Article  PubMed  CAS  Google Scholar 

  • Delini-Stula A (1983) Pharmakologie der Antidepressiva. In: Larger G, Heimann H (Hrsg) Psychopharmaka, Grundlagen und Therapie. Springer Verlag, Berlin Heidelberg New York Tokyo, pp 81–95

    Google Scholar 

  • Delini-Stula A (1987) Biochemische Klassifizierung der Antidepressiva und deren klinische Validierung. In: Simhandl Ch et al. (Hrsg) Moderne Psychiatrie, Klassifikationsprobleme in der Psychiatrie. MVP Verlag, Purkersdorf, pp 131–148

    Google Scholar 

  • Delini-Stula A, Schiwy W (1989) Verhütung von Panikattacken mit Imipramin und Clomipramin: Pharmakologische Begründung und Zusammenfassung der klinischen Befunde. In: Kielholz P, Adams P (Hrsg) Die Vielfalt von Angstzuständen. Deutscher Ärzte-Verlag, Köln, pp 177–187

    Google Scholar 

  • Eriksson EL (1987) Brain neurotransmitters in panic disorders. Acta Psych Scand [Suppl 335] 76:31–39

    Article  Google Scholar 

  • Flament MF et al. (1987) Biochemical changes during clomipramine treatment in childhood obsessive- compulsive disorder. Acta Gen Psychiatr 44 [3]:219–225

    Article  CAS  Google Scholar 

  • Healy D, Carney PA, Leonard BE (1982) Monoamine-related markers of depression: Changes following treatment. J Psych Res 17 [3]:251–260

    Article  Google Scholar 

  • Healy D, Carney PA, Leonard BE (1984) Biochemical correlates of antidepressant response. Results of a trazodone versus amitriptyline trial. Psychopathology 17 [Suppl 2]:82–87

    Article  PubMed  Google Scholar 

  • Lapin IP, Oxenkrug GF (1969) Intensification of the central serotoninergic processes as a possible determinant of the thymoleptic effect. Lancet 1:132–136

    Article  PubMed  CAS  Google Scholar 

  • Lecrubier Y, Puech AJ, Boyer P (1990) The contribution of neuropharmacology to the understanding of ill-defined psychological disorders. In: Sartorius N et al. (eds) Psychological disorders in general medical settings. Hogrefe & Huber Publ, Toronto Lewiston New York Bern Stuttgart, pp 98–110

    Google Scholar 

  • Maas JW et al. (1982) Pre-treatment neurotransmitter metabolites in response to imipramine and amitriptyline treatment. Psych Med 12:37–43

    Article  CAS  Google Scholar 

  • Maas JW et al. (1984) Pre-treatment neurotransmitter metabolite levels and response to tricyclic antidepressant drugs. Am J Psychiatr 141:1159–1171

    PubMed  CAS  Google Scholar 

  • Maitre L et al. (1980) Amine uptake inhibitors: Criteria of selectivity. In: Svensson TH, Carlsson A (eds) Biogenic amines and affective disorders. Acta Psych Scand 61 [Suppl 280]: p 97–110

    Google Scholar 

  • Maitre L et al. (1982) 5-HT uptake inhibitors: Psychopharmacological and biochemical criteria of selectivity. In: Ho BT, Schoolar JC, Usdin E (eds) Advances in biochemical psychopharmacology. Serotonin in biological psychiatry. Raven Press, New York, pp 229–246

    Google Scholar 

  • Mouret J, Lemoine P, Minuit M-P (1987) Marquers polygraphiques, cliniques et thérapeutiques des dépressions dopamine-dépendantes (DDD). CR Acad Sci, Vol 305, series III:301–306

    CAS  Google Scholar 

  • Randrup A et al. (1975) Mania, depression and brain dopamine. In: Essmann WB, Valzelli L (eds) Current developments in psychopharmacology, vol 2. Spectrum Publ, New York, pp 205–248

    Google Scholar 

  • Schildkraut JJ (1965) The catecholamine hypothesis of affective disorders: A review of supporting evidence. Am J Psychiatr 122:509–522

    PubMed  CAS  Google Scholar 

  • Timmerman L et al. (1987) A double-blind comparative clinical trial of citalopram vs maprotiline in hospitalized depressed patients. Int Clin Psychopharm 2:239–253

    Article  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1990 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Delini-Stula, A. (1990). Pharmakologische Grundlage der ‚Therapieresistenz‘ bei der Behandlung mit Antidepressiva. In: Möller, HJ. (eds) Therapieresistenz unter Antidepressiva-Behandlung. Tropon-Symposium, vol 5. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84236-8_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-84236-8_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-52765-7

  • Online ISBN: 978-3-642-84236-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics