Assessment of Burley and Dark Tobacco Alkaloids During Storage, Aging, and Fermentation
Pyridine alkaloids in tobacco (Nicotiana tabacum L.) and tobacco smoke are widely recognized for their contributions to tobacco quality and usability (Palmer 1963; Tso 1990). Nicotine is the most abundant alkaloid and may provide a pleasurable alerting effect associated with tobacco uses. The neurobiology of nicotine has been reviewed by Ashton et al. (1979). Health risks of tobacco alkaloids have also been summarized (Davis 1987). Nitrosated alkaloids may be carcinogenic (Hoffmann et al. 1987). Sums of alkaloids other than nicotine are generally small but may range up to 20% of total alkaloids (Andersen et al. 1991). Most alkaloids identified in postharvest burley and dark tobaccos or products containing them are given in Table 1. All of these compounds may be referred to as alkaloids because they occur naturally in green or processed tobacco, or they can be classified as “parent” alkaloids and their acylated, nitrosated, or oxidized derivatives. Structures of six representative tobacco alkaloids are shown in Fig. 1.
KeywordsManifold Ozone Nitrite Smoke Charcoal
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- Andersen RA, Fleming PD, Burton HR, Hamilton-Kemp TR, Hildebrand DF, Sutton TG (1990) Levels of alkaloids and their derivatives in air- and fire-cured KY 171 dark tobacco during prolonged storage: effects of temperature and moisture. Tob Sci 34:50–56Google Scholar
- Ashton H, Marsh VR, Millman JE, Rawlins MD, Stepney R, Telford R, Thomson JW (1979) Patterns of behavioral, autonomic and electrophysiological response to cigarette smoking and nicotine in man. In: Remond H, Izard C (eds) Electrophysiological effects of nicotine. Elsevier/North Holland Biomedical Press, New York, pp 159–182Google Scholar
- Davis RE (1976) A combined automated procedure for the determination of reducing surgars and nicotine alkaloids in tobacco products using a new reducing sugar method. Tob Sci 20:146–151Google Scholar
- Frankenburg WG (1950) Chemical changes in the harvested tobacco leaf. Part II. Chemical and enzymatic conversions during fermentation and aging. Adv Enzymol 10:325– 441Google Scholar
- Griffith RB (1957) The rapid determination of total alkaloids by steam distillation. Tob Sci 1:130–137Google Scholar
- Harvey WR, Stahr HM, Smith WC (1969) Automated determination of reducing sugars and nicotine alkaloids on the same extract of tobacco leaf. Tob Sci 15:13–15Google Scholar
- Palmer JK (1963) Changes in the nitrogenous constituents of burley tobacco during curing and aging. Tob Sci 7:93–96Google Scholar
- Peng Q (1990) Alkaloids, nitrates, nitrites and tobacco specific nitrosamines in dark tobacco. Masters thesis, University of Kentucky, Lexington, KYGoogle Scholar
- Spiegelhalder B, Kubacki SJ, Fischer S (1989) A method for the determination of tobacco-specific nitrosamines (TSNA), nitrate and nitrite in tobacco leaves and processed tobacco. Beitr Tabakforsch Int 14:135–144Google Scholar
- Tso TC (1990) Production, physiology, and biochemistry of tobacco plant. Ideals, Beltsville, MDGoogle Scholar
- Tso TC, Andersen RA (1974) Analysis of leaf tobacco. In: Encyclopedia of industrial chemical analysis, vol 19. John Wiley, New York, pp 133–160Google Scholar