Head and Neck Cancer

  • Samuel G. TaylorIV
  • Katherine Griem
Part of the Medical Radiology book series (MEDRAD)

Abstract

Cisplatin has been an important addition to the treatment of head and neck cancer. It is the only drug to have been proven to cause a survival benefit when compared with supportive care alone in the palliative management of advanced head and neck cancer (Morton et al. 1985). It has interesting radiation-sensitizing properties in some systems and it is part of the most active drug combination in head and neck cancer when combined with 5-ftuorouracil infusion. In comparison with the newer analogs of carboplatin and iproplatin, cisplatin has the highest tumor cell uptake of the platinates when given parenterally (Hecquet.et al. 1987).

Keywords

Toxicity Fractionation Oncol Carboplatin Vincristine 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • Samuel G. TaylorIV
    • 1
  • Katherine Griem
    • 2
  1. 1.Section of Medical OncologyRush-Presbyterian-St. Luke’s Medical CenterChicagoUSA
  2. 2.Rush-Presbyterian-St. Luke’s Medical CenterChicagoUSA

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