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Cellular Metabolic Consequences of Altered Perfusion

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Tissue Oxygen Utilization

Part of the book series: Update in Intensive Care and Emergency Medicine ((UICM,volume 12))

Abstract

The cellular metabolic and functional consequences of reduced oxygen availability have been extensively studied since the turn of the century. The knowledge of the response of the whole body or of individual organs to hypoxia was initially mainly based on analyses of substrate and intermediary metabolite levels in arterial and/or venous blood. With time analytic techniques were improved allowing detailed biochemical characterization of the metabolic situation in microsamples of tissues, isolated cells and subcellular fractions. Thereby the bulk of information on the cellular effects of shock, anoxia and ischemia grew rapidly in the 1950s and 1960s [1].

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Authors
  1. H. Haljamäe
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Editors and Affiliations

  1. Pulmonary Medicine, Health Science Center, 6431 Fannin, Suite 1274, 77030, Houston, TX, USA

    Guillermo Gutierrez

  2. Department of Intensive Care, Erasme University Hospital, Free University of Brussels, Route de Lennik 808, 1070, Brussels, Belgium

    Jean Louis Vincent (Clinical Director) (Clinical Director)

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© 1991 Springer-Verlag Berlin Heidelberg

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Haljamäe, H. (1991). Cellular Metabolic Consequences of Altered Perfusion. In: Gutierrez, G., Vincent, J.L. (eds) Tissue Oxygen Utilization. Update in Intensive Care and Emergency Medicine, vol 12. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84169-9_6

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  • DOI: https://doi.org/10.1007/978-3-642-84169-9_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-52472-4

  • Online ISBN: 978-3-642-84169-9

  • eBook Packages: Springer Book Archive

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