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Tissue Oxygen Utilization pp 41–55Cite as

Application of NIR Spectroscopy to Problems of Tissue Oxygenation

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Part of the book series: Update in Intensive Care and Emergency Medicine ((UICM,volume 12))

Abstract

Over the past few years, several new technologies have emerged with the potential to evaluate regional oxygenation and oxidative metabolism. Among these technologies are complex optical methods that have been developed primarily for the research laboratory. Optical measurements of the oxygenation of hemoglobin and myoglobin in tissue [1] reduced pyridine nucleotides [2] and the oxidation-reduction status of cytochrome c oxidase and other cytochromes [3] have been used for many years as intracellular indicators to study oxidative metabolism noninvasively. One of the newer optical techniques, Near Infrared Spectroscopy (NIRS), has shown promise as a continuous, noninvasive indicator of regional oxidative metabolism in intact tissue. We will briefly review the principles of NIR spectroscopy and indicate how we are using NIRS to investigate some of the pertinent questions about tissue oxygenation in disease states.

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Authors
  1. C. A. Piantadosi
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  2. W. J. Parsons
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  3. J. A. Griebel
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Editor information

Editors and Affiliations

  1. Pulmonary Medicine, Health Science Center, 6431 Fannin, Suite 1274, 77030, Houston, TX, USA

    Guillermo Gutierrez

  2. Department of Intensive Care, Erasme University Hospital, Free University of Brussels, Route de Lennik 808, 1070, Brussels, Belgium

    Jean Louis Vincent (Clinical Director) (Clinical Director)

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© 1991 Springer-Verlag Berlin Heidelberg

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Piantadosi, C.A., Parsons, W.J., Griebel, J.A. (1991). Application of NIR Spectroscopy to Problems of Tissue Oxygenation. In: Gutierrez, G., Vincent, J.L. (eds) Tissue Oxygen Utilization. Update in Intensive Care and Emergency Medicine, vol 12. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84169-9_4

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  • DOI: https://doi.org/10.1007/978-3-642-84169-9_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-52472-4

  • Online ISBN: 978-3-642-84169-9

  • eBook Packages: Springer Book Archive

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