Abstract
An adequate supply of oxygen is necessary for the cells of the body to efficiently produce the necessary quantities of energy, in the form of adenosine triphosphate (ATP), which is required to maintain their integrity as well as carry out the various specialized functions assigned to them. A complex interaction between the cardiovascular and respiratory systems has evolved to ensure that O2 demands can be met under conditions in which energy requirements may vary 10-fold or more. Under certain conditions, however, the limits of the system are exceeded or its ability to react to changes in the body’s needs appear to be overwhelmed. This paper will review what is known about the relationship between O2 transport (DO2) and utilization (\( \dot{V}{{O}_{2}} \)) in a number of acute and chronic disease processes.
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© 1991 Springer-Verlag Berlin Heidelberg
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Dantzker, D.R. (1991). Oxygen Delivery and Utilization in Acute and Chronic Disease. In: Gutierrez, G., Vincent, J.L. (eds) Tissue Oxygen Utilization. Update in Intensive Care and Emergency Medicine, vol 12. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84169-9_10
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DOI: https://doi.org/10.1007/978-3-642-84169-9_10
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-52472-4
Online ISBN: 978-3-642-84169-9
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