Skip to main content

Low and High Dose Rate Afterloading in Gynecological Malignancies

  • Chapter
Interventional Radiation Therapy

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

  • 115 Accesses

Abstract

Low dose rate (LDR) afterloading with a remote-controlled afterloading system is replacing the well-tried brachytherapy with radium of the past decades. Using an equivalent geometrical setup and an equivalent radioactive source, results equally as good as in radium therapy can be achieved. It has been possible with the afterloading system to introduce sources of a higher dose rate (HDR), that is, short-term irradiation in terms of minutes.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  • Becker J, Scheer KE (1952) Strahlentherapeutische Anwendung von radioaktivem Kobalt in Form von Perlen. Strahlentherapie 86: 540

    Google Scholar 

  • Chassagne D (1973) Low-dose-rate technique of endocavitary brachytherapy. Proc R Soc Med 64: 601

    Google Scholar 

  • Dale RG (1985) The application of the linear-quadratic dose effect equation to fractionated and protracted radiotherapy. Br J Radiol 58: 515–528

    Article  PubMed  CAS  Google Scholar 

  • Delouch G, Harvey P, Laval C, Rambert P, Gest J (1979) Résultats de la radiothérapie de 406 cancers du col de l’utérus (T2 distaux et T3). Bull Cancer (Paris) 66: 549

    Google Scholar 

  • Denekamp J, Fowler JF (1966) Further investigations of the response of irradiated mouse skin. International Journal of Radiation Biology 10: 435

    Article  CAS  Google Scholar 

  • Ellis F, Dose N (1969) Time and fractionation: a clinical hypothesis. Clin Radiol 20: 1–7

    Article  PubMed  CAS  Google Scholar 

  • Ellis F (1971) Nominal standard dose and the ret. Br J Radiol 44: 101

    Article  PubMed  CAS  Google Scholar 

  • Field SD, Hornsey SH (1952) Repair in normal tissues and the possivle relevance to radiotherapy. Strahlentherapie 153: 371

    Google Scholar 

  • Fletcher GH, Rutledge FN (1967) Overall results in radiotherapy for carcinoma of the cervix. Clin Obstet Gynecol 10: 958

    Article  PubMed  CAS  Google Scholar 

  • Fox M, Nias AHW (1970) The influence of recovery from sublethal damage on the response of cells to protracted irradiation at low dose-rate. Current topics in radiation research 7: 71

    CAS  Google Scholar 

  • Hall EJ (1972) Radiation dose-rate: a factor of importance in radiobiology and radiotherapy. Brit J of Radiol 45: 81

    Article  CAS  Google Scholar 

  • Hall EJ, Bedford JS (1964) Dose rate: its effect on the survival of Hela cells irradiated with gamma-rays. Radiation Research 22: 305

    Article  PubMed  CAS  Google Scholar 

  • Inque T, Hori S, Miyata L, Ozekio, Shigematsu D (1978) High versus low dose rate intracavitory irradiation of carcinoma of the uterine cervix. Acta Radiol [Oncol] (Stockh) 17: 277

    Google Scholar 

  • Kellerer AM (1977) Grundlagen der Ellis-Formel. Strahlentherapie 153: 384

    PubMed  CAS  Google Scholar 

  • Kirk J, Gray WM, Watson ER (1975a) Cumulative radiation effect. IV. Normalization of fractionated and continuous therapy — area and volume correction factors. Clin Radiol 26: 77–88

    Article  PubMed  CAS  Google Scholar 

  • Kirk J, Gray W, Watson ER (1975b) Cumulative radiation effect. V. Time gaps in treatment regimes. Clin Radiol 26: 159

    Article  Google Scholar 

  • Liversage WE (1969) A general formula for equating protracted and acute regimes of radiation. Br J Radiol 42: 432–440

    Article  PubMed  CAS  Google Scholar 

  • Morrison RA (1988) The K-effect formulas for low dose rate irradiation with gamma rays. Endocuriether Hyperthermia Oncol 4: 125–128

    Google Scholar 

  • Lindrop P, Rotbalt J (1963) In: Cellular Basis and Aetiology of Late Somatic Effects of Ionizing Radiations. Academic Press, London, p 313

    Google Scholar 

  • Orton CG (1987) What minimum number of fractions is required with high dose-rate remote afterloading (Correspondence). Br J Radiol 60: 300–301

    Article  PubMed  CAS  Google Scholar 

  • Pierquin B, Marinello G (1981) Plesiocuriethérapie des cancers du col de l’utérus. J Ent Radiother 4: 231

    Google Scholar 

  • Rotte K (1981) Ferngesteuerte Afterloadingverfahren. Strahlentherapie [Special Vol] 76: 312–320

    Google Scholar 

  • Rotte K (1983) Das ferngesteuerte Nachladeverfahren (Remote-Controlled Afterloading) für die intrakavitäre Kontakttherapie (Brachytherapie) gynäkologischer Karzinome. Radiologe 23: 20

    PubMed  CAS  Google Scholar 

  • Taina E (1981) High versus low dose rate intracavitary radiotherapy in the treatment of carcinoma of the uterus. Acta Obstet Gynecol Scand [Suppl] 103: 214

    Google Scholar 

  • Von Fournier D, Kuttig H, Kubli F, Braun K (1975) Die Anwendung von Kobalt-60-Perlen beim corpusCarcinom. Technik, Komplikation und Ergebnisse. Strahlentherapie 150: 273

    PubMed  CAS  Google Scholar 

  • Von Fournier D, Senf W, Kuttig H, Kubli F (1976) Verbesserung der gynäkologischen Radiumtherapie durch Afterloadingtechnik mit Cäsium-137. Strahlentherapie 151: 195

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1991 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

von Fournier, D., Anton, H.W., Junkermann, H., Wolf, G. (1991). Low and High Dose Rate Afterloading in Gynecological Malignancies. In: Sauer, R. (eds) Interventional Radiation Therapy. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84163-7_43

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-84163-7_43

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-84165-1

  • Online ISBN: 978-3-642-84163-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics