Skip to main content

Comparison Between High Dose Rate Afterloading and Conventional Radium Therapy

  • Chapter
Interventional Radiation Therapy

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

Abstract

Although there is a certain rivalry in primary treatment of cancer of the cervix between surgical procedures and radiotherapy, intracavitary brachytherapy will continue to play an important role. As an example, in Fig. 1 is shown to what extent the different treatment modes were applied and the shifts that occurred in the Women’s Hospital of the University of Würzburg since 1950. On the other hand there is no doubt that the radium application carried out over decades will be completely replaced by remote-controlled afterloading procedures in the near future. Remote-controlled afterloading machines and the necessary applicators have now reached such a level of technical perfection that they meet all requirements even for individual computerized tomography (CT)-based treatment planning (Bauer et al. 1981; Busch et al. 1977; Frischkorn 1976; Gauwerky 1977; Henschke et al. 1963; Herbolsheimer 1989; Himmelmann and Ragnhult 1986; Ladner 1989, Rotte 1981, 1983; Vahrson 1989; Walstam 1977).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  • Arai T, Morita S, Kutsutani Y, linuma T (1980) Relationship between total iso-effect dose and number of fractions for the treatment of uterine cervical carcinoma by high dose-rate intracavitary irradiation. Br J Radiol [Special Rep] 17: 89–92

    Google Scholar 

  • Bauer MD, von Fournier D, Fehrentz F, Kuttig H, zum Winkel K, Neldner F (1981) Afterloading-Methode zur Simulation der intrauterinen Packmethode beim Korpuskarzinom. Strahlentherapie 157: 793–800

    PubMed  CAS  Google Scholar 

  • Busch M, Makoski B, Schulz U, Sauerwein K (1977) Das Essener Nachladeverfahren für die intrakavitäre Strahlentherapie. Strahlentherapie 153: 581–588

    PubMed  CAS  Google Scholar 

  • Cohen L (1980) Biological models and computed isoeffect tables for continuous low dose-rate and intermittent fractionated radiation therapy. Br J Radiol [Special Rep] 17: 138–145

    Google Scholar 

  • Dale RG (1985) The application of the linear-quadratic dose-effect equation to fractionated and protracted radiotherapy. Br J Radiol 58: 515–528

    Article  PubMed  CAS  Google Scholar 

  • Ellis F (1971) Nominal standard dose and the ret. Br J Radiol 44: 101–108

    Article  PubMed  CAS  Google Scholar 

  • Ellis F (1980) Low to high dose-rate by the TDF system. Br J Radiol [Special Rep] 17: 146–156

    Google Scholar 

  • Fowler JF (1989) The linear quardatic formula and progress in fractionated radiotherapy a review. Br J Radiol 62: 679–694

    Article  PubMed  CAS  Google Scholar 

  • Frankendal B (1980) Afterloading technique with high dose-rate irradiation of cancer of the uterus. Br J Radiol [Special Rep] 17: 99–101

    Google Scholar 

  • Frischkorn R (1976) Gynäkologische Strahlentherapie. In: Döderlein G, Wulf KH (eds) Klinik der Frauenheilkunde und Geburtshilfe. Ein Handbuch für die Praxis, vol 2. Urban und Schwarzenberg, München, pp 501–723

    Google Scholar 

  • Gauwerky F (1977) Kurzzeit-Afterloading-Curietherapie gynäkologischer Karzinome, Technik und Problematik. Strahlentherapie 153: 793–801

    PubMed  CAS  Google Scholar 

  • Glaser FH (1986) Comparison of HDR afterloading with 192-Ir versus conventional radium therapy in cervix cancer: 5-year results and complications. In: Vahrson H, Rauthe G (eds) High dose rate afterloading in the treatment of cancer of the uterus, breast and rectum. Urban and Schwarzenberg, Munich, p 106

    Google Scholar 

  • Henschke U, Hilaris B, Mahan D (1963) Afterloading in interstitial and intracavitary radiation theapy. AJR 90: 386–395

    CAS  Google Scholar 

  • Herbolsheimer M (1989) Intrauterine packing by remote HDR-afterloading in endometrial carcinoma. In: Rotte K, Kiffer J (eds) Changes in brachytherapy. Wachholz, Nürnberg, pp 130–138

    Google Scholar 

  • Himmelmann A, Ragnhult I (1986) HDR brachytherapy with improved accuracy: results compared to those of a mannual radium system. In: Vahrson H, Rauthe G (eds) High dose rate afterloading in the treatment of cancer of the uterus, breast and rectum. Urban and Schwarzenberg, Munich p 137

    Google Scholar 

  • Joslin CAF, Smith C, Mallik A (1972) The treatment of cervix cancer using high activity sources. Br J Radiol 45: 257–270

    Article  PubMed  CAS  Google Scholar 

  • Kauppila A, Kiviniity K (1980) High dose-rate intracavitary irradiation in the treatment of cervical and endometrical carcinomas: preliminary observations. Br J Radiol [Special Rep] 17: 59–64

    Google Scholar 

  • Kinoshita M, Oncho K (1980) The use of the Cathetron in the Sawara General Hospital: the first attempt to introduce the Cathetron into Japan. Br J Radiol [Special Rep] 17: 86–88

    Google Scholar 

  • Kirk J, Gray WM, Watson ER (1971) Cumulative radiation effect. I. Fractionated treatment regimes. Clin Radiol 22: 145–155

    Article  PubMed  CAS  Google Scholar 

  • Ladner HA (1989) Comparison of the results of primary radiotherapy and radical surgery in cervical carcinoma. In: Rotte K, Kiffer J (eds) Changes in brachytherapy. Wachholz, Nürnberg, pp 99–108

    Google Scholar 

  • Liversage WE (1969) A general formula for equating protracted and acute regimes of radiation. Br J Radiol 42: 432–440

    Article  PubMed  CAS  Google Scholar 

  • Liversage WE (1971) A critical look at the ret. Br J Radiol 44: 91–100

    Article  PubMed  CAS  Google Scholar 

  • Liversage WE (1980) A comparison of the predictions of the CRE, TDF and Liversage formulae with clinical experience. Br J Radiol [Special Rep] 17: 182–189

    Google Scholar 

  • Löffler E, van der Laarse R (1988) Technique and individual afterloading treatment planning simulating classic Stockholm brachytherapy for cervix cancer. In: Vahrson H, Rauthe G (eds) High dose rate afterloading in the treatment of cancer of the uterus, breast and rectum. Urban and Schwarzenberg, Munich, pp 83–89

    Google Scholar 

  • Orton CG (1989) Biological aspects of combined radiotherapy, brachytherapy and teletherapy. In: Rotte K, Kiffer J (eds) Changes in brachytherapy. Wachholz, Nürnberg, pp 7–14

    Google Scholar 

  • Rotte K (1981) Ferngesteuerte Afterloadingverfahren. Strahlentherapie [Special Vol] 76: 313–320

    CAS  Google Scholar 

  • Rotte K (1983) Das ferngesteuerte Nachladeverfahren (Remote-Controlled Afterloading) für die intrakavitäre Kontakttherapie (Brachytherapie) gynäkologischer Karzinome. Radiologe 23: 20–23

    PubMed  CAS  Google Scholar 

  • Snelling TD, Lambert HE, Yarnold J (1980) Clinical results and complications following treatment of carcinoma of the cervix and endometrium using the Cathetron at the Middlesex Hospital. Br J Radiol [Special Rep] 17: 32–37

    Google Scholar 

  • Taina E (1981a) Complications following high and low dose-rate intracavitary radiotherapy for stage I-II cervical carcinoma: a comparison of remotely afterloaded Co60 (Cathetron) and conventional radium therapy. Acta Obstet Gynecol Scand 103: 59–66.

    Article  Google Scholar 

  • Taina E (1981b) A comparison of clinical results following high dose-rate intracavitary afterloading irradiation with Co60 (Cathetron) and conventional radium therapy for stage I-II endometrial carcinoma. Acta Obstet Gynecol Scand 103: 51–58

    Article  Google Scholar 

  • Trott KR (1975) Strahlenbiologische Überlegungen bei der Wahl der Dosisleistung in der intrakavitären Strahlentherapie. Strahlentherapie 150: 261–265

    PubMed  CAS  Google Scholar 

  • Trott KR (1978) Der Einfluß der Dosisleistung auf die therapeutische Wirkung von 61Co-Gammabestrahlung beim Adenokarzinom der Maus. Strahlentherapie 154: 656–658

    PubMed  CAS  Google Scholar 

  • Turesson I, Notter G (1980) An experimental study of single and fractionated high dose-rate and continuous low dose-rate irradiation on normal tissue. Br J Radiol [Special Rep] 17: 165–177

    Google Scholar 

  • Vahrson H (1989) Clinical experience with fractionated high dose rate-afterloading brachytherapy in carcinoma of the cervix. In: Rotte K, Kiffer J (eds) Changes in brachytherapy. Wachholz, Nürnberg, pp 108–117

    Google Scholar 

  • Walstam R (1977) Strahlenphysikalische Voraussetzungen der ferngesteuerten Afterloadbestrahlung. Strahlentherapie 153: 802–806

    PubMed  CAS  Google Scholar 

  • Wyckoff HO (1985) Dose and volume specification for reporting intracavitary therapy in gynecology. International Commission on Radiation Units and Measurements, Bethesda (ICRU report no 38 )

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1991 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Rotte, K. (1991). Comparison Between High Dose Rate Afterloading and Conventional Radium Therapy. In: Sauer, R. (eds) Interventional Radiation Therapy. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84163-7_41

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-84163-7_41

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-84165-1

  • Online ISBN: 978-3-642-84163-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics