The Cre-lox Recombination System

  • R. H. Hoess
  • K. Abremski
Part of the Nucleic Acids and Molecular Biology book series (NUCLEIC, volume 4)


Over the past 10 years considerable progress has been made in elucidating the biochemical events involved in site-specific recombination. Information has been gathered from a number of well-characterized systems, most notably the bacteriophage λ Int system which has long served as the paradigm for site-specific recombination. A review covering the site-specific recombination field has recently been published (Craig 1988). This review focuses on the well-characterized Cre-lox site-specific recombination system of bacteriophage P1.


Inverted Repeat Space Region Recombination System Strand Exchange Recombination Pathway 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • R. H. Hoess
  • K. Abremski
    • 1
  1. 1.Central Research and Development DepartmentE. I. du Pont de Nemours & Co.WilmingtonUSA

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