Glioma pp 37-55 | Cite as

Modern Imaging for Cerebral Gliomas: Breakthroughs and Limitations

  • M. C. Kaiser
  • J. H. Kralendonk
Conference paper


Proper diagnosis and optimal treatment planning of cerebral gliomas can be achieved only if reliable diagnostic imaging techniques are available. In the past, neurologic physical examination was complemented by pneumoen­cephalography, angiography, and radionuclide study. These investigations provided only limited information about site, size, and extent of the tumor; patterns of malignant vascularization could be recognized, and a hint as to the aggressive behavior of the lesion (compromised blood-brain barrier) could be derived. These were relatively invasive methods, causing patient discomfort and entailing high costs of hospitalization.


Magnetic Resonance Imaging Study Stereotactic Biopsy Cerebral Glioma Plain Computerize Tomography Control Computerize Tomography 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Beahrs OH, Meyers MH (eds) (1983) Manual staging of cancer, 2nd edn. Lippincott, PhiladelphiaGoogle Scholar
  2. 2.
    Bird CR, Drayer BP, Medina M et al. (1988) Gd-DTPA enhanced MR imaging in pediatric patients after brain tumor resection. Radiology 169: 123–126PubMedGoogle Scholar
  3. 3.
    Chisholm RA, Stenning S, Hawkins TD (1989) The accuracy of volumetric measurement of high-grade gliomas. Clin Radio! 40: 17–21CrossRefGoogle Scholar
  4. 4.
    Curnes JT, Laster DW, Ball MR et al. (1986) Magnetic resonance imaging of radiation injury to the brain. AJNR 7: 389–394Google Scholar
  5. 5.
    DeLaPaz RL, New PFJ, Buonanno FS et al. (1984) NMR imaging of intracranial hemorrhage. J Comput Assist Tomogr 4: 599–607CrossRefGoogle Scholar
  6. 6.
    Destian S, Sze G, Krol G et al. (1989) MR imaging of hemorrhagic intracranial neoplasms. AJR 152: 137–144PubMedGoogle Scholar
  7. 7.
    DiChiro G, DeLaPaz RL, Brooks PA et al. (1982) Glucose utilization of cerebral gliomas measured by F15 fluorodeoxyglucose and positron emission tomography. Neurology (N4) 32: 291–292Google Scholar
  8. 8.
    Edelman RR, Johnson K, Buxton R et al. (1986) MR of hemorrhage: a new approach. AJNR 7: 751–756PubMedGoogle Scholar
  9. 9.
    Gibby WA (1988) MR contrast agents. An overview. Radiol Clin North Am 26: 1047–1058PubMedGoogle Scholar
  10. 10.
    Gumori JM, Grossman RI, Goldberg HI et al. (1985) Intracranial hematomas: imaging by high-field MRI. Radiology 157: 87–93Google Scholar
  11. 11.
    Hatanaka H, Sano K, Kitamura K et al. (1984) CT findings in patients with gliomas súrviving more than ten years. Neurochirurgia (Stuttg) 27: 106–110Google Scholar
  12. 12.
    Hermanek P, Sobin LH (eds) (1987) TNM classification of malignant tumors, 4th edn. Springer, Berlin Heidelberg New YorkGoogle Scholar
  13. 13.
    Johnson PC, Hunt SJ, Drayer BP (1989) Human cerebral gliomas: correlation of postmortem MR imaging and neuropathologic findings. Radiology 170: 211–217PubMedGoogle Scholar
  14. 14.
    Kaiser MC, Ramos L (1990) MRI of the spine. A guide to clinical applications. Thieme, StuttgartGoogle Scholar
  15. 15.
    Karim ABMF, Rutten EHJM, Gonzalez DG, Horiot JC, van der Schueren E, Svoboda V, van Alphen HAM, Heimans JJ, Thomas DGT, Aaronson NK (1985) A randomized trial on dose response in radiation therapy of the cerebral gliomas (low-grade astrocytoma and oligodendroglioma) of the adult. EORTC, Brussels (Protocol no 22844 )Google Scholar
  16. 16.
    Karlsson UL, Brady LW (1987) Primary intracranial neoplasms. In: Perez CA, Brady LW (eds) Principles and practice of radiation oncology. Lippincott, Philadelphia, pp 408–436Google Scholar
  17. 17.
    Lee Y-Y, van Tassel P (1989) Intracranial oligodendrogliomas: imaging findings in 35 untreated cases. AJR 152: 361–369PubMedGoogle Scholar
  18. 18.
    Maurer AH (1988) Nuclear medecine: SPECT comparisons to PET. Radiol Clin North Am 26: 1059–1074PubMedGoogle Scholar
  19. 19.
    Mosskin M, Erikson K, Hindmarsh T et al. (1989) Positron emission tomography compared with magnetic resonance imaging and computed tomography in supratentorial gliomas using multiple stereotactic biopsies as reference. Acta Radiol (Stockh) 30: 225–232CrossRefGoogle Scholar
  20. 20.
    Schörner W, Laniado M, Kornmesser W, Felix R (1989) Comparison of multi-echo and contrast-enhanced MR scans: image contrast and delineation of intracranial tumors. Neuroradiology 31: 140–147PubMedCrossRefGoogle Scholar
  21. 21.
    Szuwart U, Beunefeld H, Behr H (1989) Classification of gliomas and medulloblastomas using the new TNM system for cerebral tumors. Neurosurg Rev 12: 233–238PubMedCrossRefGoogle Scholar
  22. 22.
    Warburg O (1930) The metabolism of tumors. Constable, LondonGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • M. C. Kaiser
  • J. H. Kralendonk

There are no affiliations available

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