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Update 1990 pp 586-592 | Cite as

Acidosis in CPR: Pathophysiology and Treatment

  • M. von Planta
Conference paper
Part of the Update in Intensive Care and Emergency Medicine book series (UICM, volume 10)

Abstract

During cardiac arrest and cardio-pulmonary resuscitation (CPR) only limited blood flow and consequently organ perfusion can be maintained by chest compression. Cardiac output during CPR averages only 25 to 35% of normal and thus severely reduces oxygen delivery to the tissues. The metabolism therefore turns to its energetic emergency pathway resulting in the production of anaerobic metabolites. The buildup of lactic acid is slow, while the CO2 concentration rapidly increases during CPR. After onset of cardiac arrest intramyocardial CO2 progressively increases to levels exceeding 400 mmHg. These increases in CO2 can only be reversed by improving coronary blood flow and its associated oxygen delivery.

Keywords

Cardiac Arrest Cardiopulmonary Resuscitation Coronary Blood Flow Chest Compression Limited Blood Flow 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • M. von Planta

There are no affiliations available

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