Update 1990 pp 472-477 | Cite as

Management of the Acute Neuropsychiatric Manifestations of Cocaine Intoxication

  • L. Goldfrank
Conference paper
Part of the Update in Intensive Care and Emergency Medicine book series (UICM, volume 10)


Cocaine users in North America, South America and Europe number in the millions on a daily basis. The neuropsychiatrie manifestations of cocaine intoxication are often an exaggeration of the sought after clinical manifestations and represent the commonest causes of visits to hospital settings. Of the thousands of patients who present to the Bellevue Emergency Department with cocaine intoxication annually approximately two-thirds have neuropsychiatrie compromise. These complications included an altered mental status, seizures, agitation, suicidal ideation and cerebrovascular accidents. The prevalence of cocaine use has become so substantial that almost all patients from adolescence to adulthood presenting to the emergency department with these symptoms are considered to potentially have used cocaine and become intoxicated with the agent. During the first 11 months of 1986, 935 persons died in the city of New York with evidence of cocaine in their bodies [1]. This represented 15% of all patients brought to the Office of the Chief Medical Examiner. Neuropsychiatrie abnormalities were a common cause of death: 38% died of homicide, 7% of suicide, 8% of “accidents”, and 2% of cerebral hemorrhage. Of these patients 86.9% were between the ages of 11–44 years of age [1].


Calcium Channel Blocker Acute Tubular Necrosis Cocaine Abuse Cocaine User Alcohol Withdrawal Syndrome 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

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  • L. Goldfrank

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