Update 1990 pp 252-259 | Cite as

Measurement of the Work of Breathing in the Mechanically Ventilated Patient

  • J. Mancebo
Conference paper
Part of the Update in Intensive Care and Emergency Medicine book series (UICM, volume 10)


Work, in physics, means to apply a force through a distance and in a solid system, work is performed when this force moves its point of application across a determined length. When the physical system is a fluid, work is performed when a pressure changes the volume of the system. The relation is as follows: Work (W) = Pressure (P) × Volume (V) [1–3].


Chest Wall Respiratory Muscle Inspiratory Flow Inspiratory Muscle Transpulmonary Pressure 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Otis AB (1964) The work of breathing. In: Fenn WO, Rahn H (eds) Handbook of physiology, Sect 3, vol I. American Physiological Society, Washington DC, pp 463–476Google Scholar
  2. 2.
    Roussos C (1985) Energetics. In: Roussos C, Macklem PT (eds) The thorax: Part A. Dekker, New York, pp 437–492Google Scholar
  3. 3.
    Roussos C, Campbell EJM (1986) Respiratory muscle energetics. In: Fishman AP, Macklem PT, Mead J (eds) Handbook of physiology. Sect 3, vol III (Mechanics of breathing, Part 2). American Physiological Society, Bethesda, pp 481–509Google Scholar
  4. 4.
    Marini JJ, Capps JS, Culver BH (1985) The inspiratory work of breathing during assisted mechanical ventilation. Chest 87:612–618PubMedCrossRefGoogle Scholar
  5. 5.
    Marini J J, Rodriguez M, Lamb V (1986) Bedside estimation of the inspiratory work of breathing during mechanical ventilation. Chest 89:56–60PubMedCrossRefGoogle Scholar
  6. 6.
    Marini JJ, Rodriguez M, Lamb V (1986) The inspiratory workload of patient-initiated mechanical ventilation. Am Rev Respir Dis 134:902–909PubMedGoogle Scholar
  7. 7.
    Harf A, Atlan G (1975) Travail ventilatoire. Rev Fr Mai Resp 3:795–802Google Scholar
  8. 8.
    Mead J, Smith JC, Loring SH (1985) Volume displacements of the chest wall and their mechanical significance. In: Roussos C, Macklem PT (eds) The thorax: Part A. Dekker, New York, pp 369–392Google Scholar
  9. 9.
    Brochard L, Harf A, Lorino H, Lemaire F (1989) Inspiratory pressure support prevents diaphragmatic fatigue during weaning from mechanical ventilation. Am Rev Respir Dis 139:513–521PubMedCrossRefGoogle Scholar
  10. 10.
    Truwit JD, Marini JJ (1988) Evaluation of thoracic mechanics in the ventilated patient. Part II: Applied mechanics. J Crit Care 3:199–213CrossRefGoogle Scholar
  11. 11.
    Baydur A, Behrakis PK, Zin WA, Jaeger M, Milic-Emili J (1982) A simple method for assessing the validity of the esophageal balloon technique. Am Rev Respir Dis 126:788–791PubMedGoogle Scholar
  12. 12.
    Agostoni E, D’Angelo E (1985) Statics of the chest wall. In: Roussos C, Macklem PT (eds) The thorax: Part A. Dekker, New York, pp 259–295Google Scholar
  13. 13.
    Fleury B, Murciano D, Talamo D, Aubier M, Pariente R, Milic-Emili J (1985) Work of breathing in patients with chronic obstructive pulmonary disease in acute respiratory failure. Am Rev Respir Dis 131:822–827PubMedGoogle Scholar
  14. 14.
    Boyer F, Robert D, Gaussorgues P, Piperno D (1987) Le travail des muscles respiratoires. Définitions et mesures. In: Société de Réanimation de Langue Française (ed) Fonction diaphragmatique. Travail respiratoire. Expansion Scientifique Française, Paris, pp 79–102Google Scholar
  15. 15.
    Smith TC, Marini JJ (1988) Impact of PEEP on lung mechanics and work of breathing in severe airflow obstruction. J Appl Physiol 65:1488–1499PubMedGoogle Scholar
  16. 16.
    Pride NB, Macklem PT (1986) Lung mechanics in disease. In: Fishman AP, Macklem PT, Mead J (eds) Handbook of physiology. Sect 3, vol III (Mechanics of breathing, Part 2). American Physiological Society, Bethesda, pp 659–692Google Scholar
  17. 17.
    Fiastro JF, Habib MP, Shon BY, Campbell SC (1988) Comparison of standard weaning parameters and the mechanical work of breathing in mechanically ventilated patients. Chest 94:232–238PubMedCrossRefGoogle Scholar
  18. 18.
    Mancebo J, Brochard L, Amaro P, Harf A, Lemaire F (1989) Effect of inhaled bronchodilators on the work of breathing in intubated patients weaning from mechanical ventilation (Abstract). Am Rev Respir Dis 139. A97Google Scholar
  19. 19.
    Sassoon CSH, Mahutte CK, Te TT, Simmons DH, Light RW (1988) Work of breathing and airway occlusion pressure during assist-mode mechanical ventilation. Chest 93:571–576PubMedCrossRefGoogle Scholar
  20. 20.
    Capps JS, Ritz R, Pierson DJ (1987) An evaluation, in four ventilators, of characteristics that affect work of breathing. Respir Care 32:1017–1024Google Scholar
  21. 21.
    Banner MJ, Downs JB, Kirby RR, Smith RA, Boysen PG, Lampotang S (1988) Effects of expiratory flow resistance on inspiratory work of breathing. Chest 93:795–799PubMedCrossRefGoogle Scholar
  22. 22.
    Wright PE, Marini JJ, Bernard GR (1989) In vitro versus in vivo comparison of endotracheal tube airflow resistance. Am Rev Respir Dis 140:10–16PubMedCrossRefGoogle Scholar
  23. 23.
    Beydon L, Chasse M, Harf A, Lemaire F (1988) Inspiratory work of breathing during spontaneous ventilation using demand valves and continuous flow systems. Am Rev Respir Dis 138:300–304PubMedGoogle Scholar
  24. 24.
    Brochard L, Mollo JL, Mancebo J, Amaro P, Lemaire F, Harf A (1989) Comparison of the efficacy of inspiratory pressure support delivered by three ventilators (Abstract). Am Rev Respir Dis 139:A361CrossRefGoogle Scholar

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© Springer-Verlag Berlin Heidelberg 1990

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  • J. Mancebo

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