Update 1990 pp 22-31 | Cite as

Multiple Organ Failure Syndrome: Patterns and Effect of Current Therapy

  • F. B. Cerra
  • F. Negro
  • S. Eyer
Part of the Update in Intensive Care and Emergency Medicine book series (UICM, volume 10)


The Syndrome of Multiple Organ Failure (MOFS) has been described as the sequential failure of lung, liver and kidney following injury [1–11]. Historically, the MOFS was described as a response pattern following polytrauma [1–7]. Since then, it has been described after a variety of surgical pathologies including: sepsis and septic shock, hypovolemic shock as in ruptured aneurysms, and following persistent inflammation, as in pancreatitis [8–12]. It is also felt to be the most common reason associated with surgical intensive care units (SICU) stays over 5 days and to be the major cause of death in these patients today [12, 13].


Serum Bilirubin Surgical Intensive Care Unit Multiple System Organ Failure Septic Episode Death Pattern 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • F. B. Cerra
  • F. Negro
  • S. Eyer

There are no affiliations available

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