Multiple Organ Failure Syndrome: Patterns and Effect of Current Therapy
The Syndrome of Multiple Organ Failure (MOFS) has been described as the sequential failure of lung, liver and kidney following injury [1–11]. Historically, the MOFS was described as a response pattern following polytrauma [1–7]. Since then, it has been described after a variety of surgical pathologies including: sepsis and septic shock, hypovolemic shock as in ruptured aneurysms, and following persistent inflammation, as in pancreatitis [8–12]. It is also felt to be the most common reason associated with surgical intensive care units (SICU) stays over 5 days and to be the major cause of death in these patients today [12, 13].
KeywordsSerum Bilirubin Surgical Intensive Care Unit Multiple System Organ Failure Septic Episode Death Pattern
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