Follicular Center Cell Lymphoma, Mouse

  • Paul K. Pattengale
Part of the Monographs on Pathology of Laboratory Animals book series (LABORATORY)


Early lesions are whitish in color and are confined initially to the white pulp of the spleen. With time the lesions progress to confluence, first in the spleen, and later in the lymph nodes, liver, lungs, and kidneys (Pattengale and Frith 1983; Pattengale and Taylor 1983; Pattengale and Frith 1986; see also p. 137, this volume).


Reticulum cell sarcoma, type B B cell lymphoma follicular center cell lymphoma, large, small, or mixed cell lymphoma, mixed or pleomorphic 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Dunn TB (1954) Normal and pathologic anatomy of the reticular tissue in laboratory mice, with a classification and discussion of neoplasms. JNCI 14: 1281–1433PubMedGoogle Scholar
  2. Dunn TB, Deringer MK (1968) Reticulum cell neoplasm, type B, or the “Hodgkin’s-like lesion” of the mouse. JNCI 40: 771–820PubMedGoogle Scholar
  3. Fredrickson TN, Morse HC III, Yetter RA, Rowe WP, Hartley JW, Pattengale PK (1985) Multiparameter analyses of spontaneous nonthymic lymphomas occurring in NFS/N mice congeneic for ecotropic murine leukemia viruses. Am J Pathol 121: 349–360PubMedGoogle Scholar
  4. Pattengale PK, Frith CH (1983) Immunomorphologic classification of spontaneous lymphoid cell neoplasms occurring in female BALB/c mice. JNCI 70: 169–179PubMedGoogle Scholar
  5. Pattengale PK, Frith CH (1986) Contributions of recent research to the classification of lymphoid cell neoplasms in mice. CRC Crit Rev Toxicol 16: 185–212CrossRefGoogle Scholar
  6. Pattengale PK, Taylor CR (1983) Experimental models of lymphoproliferative disease: the mouse as a model for human non-Hodgkin’s lymphomas and related leukemias. Am J Pathol 113: 237–265PubMedGoogle Scholar
  7. Wogan GN (1984) Tumors of the mouse hematopoietic system: their diagnosis and interpretation in safety evaluation tests. Report of a study group. CRC Crit Rev Toxicol 13: 161–181CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • Paul K. Pattengale

There are no affiliations available

Personalised recommendations