Hemobartonellosis and Eperythrozoonosis
The phagocytic elements of the spleen, liver, lymph nodes, and other organs appear to be primarily responsible for limiting the multiplication of these parasites. Splenic macrophages are especially important in suppressing the infections, and splenomegaly is often the first and only readily apparent gross pathologic lesion of latent infection. Following experimental injection with E. coccoides (Baker et al. 1971), peak splenic enlargement of 3–4 times normal occurs approximately 7 days after infection but diminishes rapidly during the enusing week and reaches a plateau at 1.5–2 times normal by 21 days. This level of splenomegaly persisted for the remainder of a 42-day observation period. Splenomegaly is also a prominent gross pathologic sign of H. muris infection in rats; however, quantitative data are lacking.
KeywordsHepatitis Filtration Albumin Sedimentation Anemia
Unable to display preview. Download preview PDF.
- Cassell GH, Lindsey JR, Baker HJ, Davis JK (1979) Mycoplasma and rickettsial diseases. In: Baker HJ, Lindsey JR, Weisbroth SH (eds) The laboratory rat, vol I. Academic, New York, pp 259–269Google Scholar
- Moulder JW (1974) The rickettsias. In: Buchanan RE, Gibbons NE (eds) Bergey’s manual of determinative bacteriology, 8th edn. Williams and Wilkins, Baltimore, pp 882–925Google Scholar
- Wigand R (1958) Morphologische biologische und serologische Eigenschaften der Bartonellen. Thieme, StuttgartGoogle Scholar