GTP-Binding Proteins associated with CNS Myelin
The unexpected discovery of cholinergic receptor activity (Larocca et al, 1987) in isolated myelin and the abundant, dynamic metabolism of polyphos-phoinositides of PNS and CNS myelin (Kahn and Morell, 1988; Eichberg et al 1989) is forcing a reevaluation of the role of this membranous organelle in the nervous system. Implicit in these considerations is the probable participation of GTP-binding proteins (G proteins) in the signal transduction apparatus.
KeywordsMyelin Basic Protein Cholera Toxin Pertussis Toxin Myelin Protein Crude Membrane Fraction
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