Oxygen Transport and Oxygen Uptake on the Summit of Mount Everest
Why go to the trouble, time, and expense of organizing a medical research ex pedition to the summit of Mount Everest? The reason is an interest in how the human body tolerates extreme oxygen deprivation. Every physician who works in the intensive care environment, or sees patients with severe lung disease, knows that a common problem is severe hypoxemia. Our hope was that by looking at normal man under conditions of extremely severe oxygen lack, we could better understand how a patient can tolerate the hypoxemia of severe lung disease.
KeywordsMaximal Oxygen Uptake Barometric Pressure Respiratory Alkalosis Pulmonary Capillary Severe Lung Disease
Unable to display preview. Download preview PDF.
- Bencowitz HZ, Wagner PD, West JB (1982) Effect of change in P50 on exercise tolerance at high altitude: a theoretical study. J Appl Physiol: Respir Environ Exerc Physiol 53:1487–1495Google Scholar
- Bert P (1943) Barometric pressure. Researches in experimental physiology. College Book, Columbus/Oh. Translation of: La pression barométrique. Masson, Paris, 1878Google Scholar
- Blume FD, Boyer SH, Braverman LE, Cohen A (1984) Impaired osmoregulation at high altitude. J AMA 252:1580–1585Google Scholar
- Gonzales NC, Clancy RL, Albrecht T (1988) Compensation of hypocapnic alkalosis in duced after acclimatization to simulated altitude in rats. Physiologist 3I:AI46 (abstr)Google Scholar
- West JB (1985) Everest the testing place. McGraw-Hill, New YorkGoogle Scholar
- West JB, Boyer SJ, Graber DJ, Hackett PH, Maret KH, Milledge JS, Peters RM Jr, Pizzo CJ, Samaja M, Sarnquist FH, Schoene RB, Winslow RM (1983 a) Maximal exercise at extreme altitudes on Mount Everest. J Appl Physiol: Respir Environ Exerc Physiol 55:688–698Google Scholar
- West JB, Hackett PH, Maret KH, Milledge JS, Peters RM Jr, Pizzo CJ, Winslow RM (1983 b) Pulmonary gas exchange on the summit of Mt Everest. J Appl Physiol: Respir Environ Exerc Physiol 55:678–687Google Scholar
- West JB, Lahiri S, Maret KH, Peters RM Jr, Pizzo CJ (1983 c) Barometric pressures at extreme altitudes on Mt. Everest: physiological significance. J Appl Physiol: Respir Environ Exerc Physiol 54:1188–1194Google Scholar